This grant, offered by the NHLBI, is for participating in the MAPGen consortium, which aims to define common mechanism-associated traits across organ systems. Utilizing evolving knowledge of cellular and molecular networks, this grant seeks to redefine diseases based on pathogenetic mechanisms and phenotype individuals by their pathobiology, moving beyond clinical presentation. This approach will establish the basis for developing mechanism-based strategies for prevention, diagnosis, and treatment tailored to individual patients. This funding opportunity encourages applications for research centers to join the consortium. It complements a separate grant for the MAPGen Knowledge Base and Coordination Center. The NHLBI anticipates awarding 6-8 Research Centers, contributing to a total project funding of up to $25 million for MAPGen.
Opportunity ID: 52077
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-HL-11-005 |
| Funding Opportunity Title: | Cross Organ Mechanism-Associated Phenotypes for Genetic Analyses of Heart, Lung, Blood, and Sleep Diseases (MAPGen for HLBS) Research Centers (U01) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Cooperative Agreement |
| Category of Funding Activity: | Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.233 — National Center on Sleep Disorders Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Feb 24, 2010 |
| Last Updated Date: | – |
| Original Closing Date for Applications: | Sep 01, 2010 |
| Current Closing Date for Applications: | Sep 01, 2010 |
| Archive Date: | Oct 02, 2010 |
| Estimated Total Program Funding: | $25,000,000 |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Special district governments County governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education State governments Independent school districts Others (see text field entitled “Additional Information on Eligibility” for clarification) Small businesses Private institutions of higher education Public housing authorities/Indian housing authorities Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Public and State controlled institutions of higher education City or township governments Native American tribal governments (Federally recognized) Native American tribal organizations (other than Federally recognized tribal governments) For profit organizations other than small businesses |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | Purpose. The purpose of this FOA issued by the NHLBI, National Institutes of Health, is to invite applications to participate in the MAPGen consortium. This consortium seeks to utilize evolving knowledge of cellular and molecular networks to define common mechanism-associated traits across organ systems. The ultimate goal is to re-define disease at the level of pathogenetic mechanisms and phenotype individuals based on pathobiology, rather than clinical presentation. This approach will provide the basis for the development of mechanism-based strategies for prevention, diagnosis and treatment in individual patients. This FOA encourages applications for research centers and runs in parallel with a separate FOA that solicits applications for the MAPGen Knowledge Base and Coordination Center (MAPGenKB) (see HL-11-004). Mechanism of Support. This FOA will utilize the Cooperative Agreement (U01) award mechanism. Funds Available and Anticipated Number of Awards. The total amount of funding to be awarded for MAPGen (the Research Centers and the MAPGenKB) will be a maximum of $25 million for the project period. It is anticipated that 6-8 Research Centers, under this FOA, and 1 MAPGenKB under the related FOA (see HL-11-004) will be awarded. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/rfa-files/RFA-HL-11-005.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV Email:FBOWebmaster@OD.NIH.GOV |
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