The Department of Defense (DoD) is offering the FY10 Prostate Cancer Population-Based Research Award. This grant supports high-impact, population-based approaches aiming to significantly contribute to eliminating death and suffering from prostate cancer. The purpose of this award is to generate unique information and tools through statistical analysis of defined patient populations. Eligible studies include retrospective, prospective, case control, or cohort designs, requiring sufficient sample size for statistical significance and clear statistical expertise. Permitted research areas include biomarkers, epidemiology, genomics, and health disparity. Research involving human subjects is allowed, but clinical trials are excluded. Applicants must demonstrate impact, a robust statistical plan, access to target populations, and provide preliminary data.
Opportunity ID: 52286
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | W81XWH-10-PCRP-PBRA |
| Funding Opportunity Title: | DoD Prostate Cancer Population-Based Research Award |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Cooperative Agreement Grant |
| Category of Funding Activity: | Science and Technology and other Research and Development |
| Category Explanation: | – |
| Expected Number of Awards: | 3 |
| Assistance Listings: | 12.420 — Military Medical Research and Development |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Mar 02, 2010 |
| Last Updated Date: | – |
| Original Closing Date for Applications: | May 26, 2010 |
| Current Closing Date for Applications: | May 26, 2010 |
| Archive Date: | Jun 25, 2010 |
| Estimated Total Program Funding: | $2,900,000 |
| Award Ceiling: | $0 |
| Award Floor: | $0 |
Eligibility
| Eligible Applicants: | Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled “Additional Information on Eligibility” |
| Additional Information on Eligibility: | – |
Additional Information
| Agency Name: | Dept. of the Army — USAMRAA |
| Description: | The PCRP Population-Based Research Award mechanism was first offered as the Population-Based Idea Development Award in FY09. Thirty-one applications were received, and none were recommended for funding. The award mechanism has been modified for FY10. The FY10 Population-Based Research Award mechanism supports high-impact, population-based approaches to prostate cancer research. These studies, if successful, should contribute significantly to the elimination of death and suffering from prostate cancer. Proposed research must be responsive to at least one of the FY10 PCRP overarching challenges and at least one of the focus areas. The overall goal of this award is to generate unique information and/or tools that can only be achieved from the perspective of statistical analysis of a defined patient population. Applications may propose retrospective, prospective, case control, cohort, or other population-based study designs, provided the population sample is of sufficient size to demonstrate statistical significance. The study should address a well developed hypothesis that is conceptually sound and specific for prostate cancer. The statistical expertise of the study team should be clearly described and evident in the study plan. It is expected that investigators will demonstrate appropriate access to the population(s) needed for the study. Research proposed under the Population-Based Research Award may include the following areas: Biomarkers Predictors of response to therapy Disease aggressiveness Epidemiology Genomics (germline or somatic) Health disparity Molecular genetics Risk prediction Research involving human subject use is permitted under this funding opportunity, but is restricted to studies without clinical trials. In general, a clinical trial is defined as a prospective study where an intervention (e.g., device, drug, behavioral, surgical procedure, or other) is tested on human subjects for a measurable outcome. Refer to the General Application Instructions, Appendix 5, for additional information about studies involving human subjects, human subjects data, or human anatomical substances. It is the responsibility of the Principal Investigator (PI) to clearly and explicitly articulate how the project addresses the following important aspects of the Population-Based Research Award: 1. Impact: Research that has high impact will, if successful, significantly accelerate the elimination of death and suffering from prostate cancer. 2. Statistical plan: A robust statistical plan is required and should be supported with requisite statistical expertise in the study team. DOD FY10 Prostate Cancer Population-Based Research Award 4 3. Human subject plan: Applicants should provide documentation demonstrating access to, and ability to recruit, the appropriate population(s) or patient samples in numbers sufficient to achieve statistical significance. 4. Preliminary data: The presentation of preliminary data to support the study feasibility is required. Any preliminary data provided should be from the laboratory of the PI or member(s) of the collaborating team. 5. Responsiveness to PCRP overarching challenges and focus areas: The relevance of the research problem to at least one of the PCRP overarching challenges and at least one of the PCRP focus areas. |
| Link to Additional Information: | – |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
PA HELP: 301-619-7079; cdmrp.pa@amedd.army.mil
eReceipt HELP: 301-619-5507; help@cdmrp.org Email:cdmrp.pa@amedd.army.mil |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
Folder 52286 Full Announcement-1 -> fy10 cdmrp detailed budget and justification form-1.pdf
Folder 52286 Full Announcement-1 -> fy10 cdmrp biosketch-1.pdf
Folder 52286 Full Announcement-1 -> pcrp_fy10_pbra_pa_final.pdf
Packages
| Agency Contact Information: | PA HELP: 301-619-7079; cdmrp.pa@amedd.army.mil eReceipt HELP: 301-619-5507; help@cdmrp.org Email: cdmrp.pa@amedd.army.mil |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| 12.420 | PKG00016829 | Mar 02, 2010 | May 26, 2010 | View |
Package 1
Mandatory forms
52286 RR_SF424_1_2-1.2.pdf
52286 PerformanceSite_1_4-1.4.pdf
52286 RR_KeyPersonExpanded_1_2-1.2.pdf
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