The NIH HEAL Initiative is offering this grant to support vital research focused on identifying new druggable targets and discovering optimizable probes. This grant is specifically for the purpose of developing safe and efficacious medications designed to prevent and effectively treat opioid use disorders (OUDs), mitigate opioid overdose, and address complex opioid-polysubstance use comorbidities. As a core component of the NIH Helping to End Addictions Long-term (HEAL) initiative, this funding opportunity aims to significantly accelerate the development of novel medications. These innovations are crucial for addressing all critical aspects of the opioid addiction cycle, encompassing progression to chronic use, managing withdrawal, reducing craving, preventing relapse, and intervening in overdose.
Opportunity ID: 349403
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-DA-24-063 |
| Funding Opportunity Title: | HEAL Initiative: Novel Targets for Opioid Use Disorders and Opioid Overdose (R01 Clinical Trial Not Allowed) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Education Health Income Security and Social Services |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.213 — Research and Training in Complementary and Integrative Health |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Jul 19, 2023 |
| Last Updated Date: | Jul 19, 2023 |
| Original Closing Date for Applications: | Feb 01, 2024 |
| Current Closing Date for Applications: | Feb 01, 2024 |
| Archive Date: | Mar 08, 2024 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | $400,000 |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | County governments City or township governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Private institutions of higher education Independent school districts Small businesses Others (see text field entitled “Additional Information on Eligibility” for clarification) For profit organizations other than small businesses State governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Public housing authorities/Indian housing authorities Public and State controlled institutions of higher education Special district governments Native American tribal organizations (other than Federally recognized tribal governments) Native American tribal governments (Federally recognized) |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | The purpose of this notice of funding opportunity (NOFO) is to support research focusing on the identification of druggable new targets and discovery of optimizable probes for development of safe and efficacious medications to prevent and treat opioid use disorders (OUDs), opioid overdose, and opioid-polysubstance use comorbidities. This notice of funding opportunity is part of the NIH Helping to End Addictions Long-term (HEAL) initiative to accelerate the development of novel medications to treat all aspects of the opioid addiction cycle, including progression to chronic use, withdrawal symptoms, craving, relapse, and overdose. |
| Link to Additional Information: | https://grants.nih.gov/grants/guide/rfa-files/RFA-DA-24-063.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH Grants Information
grantsinfo@nih.gov Email:grantsinfo@nih.gov |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
Folder 349403 Full Announcement-RFA-DA-24-063 -> RFA-DA-24-063-Full-Announcement.pdf
Packages
| Agency Contact Information: | NIH Grants Information grantsinfo@nih.gov Email: grantsinfo@nih.gov |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-H | Use for due dates on or after January 25, 2023 | PKG00282603 | Jan 01, 2024 | Feb 01, 2024 | View |
Package 1
Mandatory forms
349403 RR_SF424_5_0-5.0.pdf
349403 PHS398_CoverPageSupplement_5_0-5.0.pdf
349403 RR_OtherProjectInfo_1_4-1.4.pdf
349403 PerformanceSite_4_0-4.0.pdf
349403 RR_KeyPersonExpanded_4_0-4.0.pdf
349403 PHS398_ResearchPlan_5_0-5.0.pdf
349403 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
349403 RR_Budget_3_0-3.0.pdf
349403 RR_SubawardBudget30_3_0-3.0.pdf
349403 PHS398_ModularBudget_1_2-1.2.pdf
349403 PHS_AssignmentRequestForm_3_0-3.0.pdf