This grant is for the purpose of deeply understanding how sleep deficiency and circadian disruption impact metabolic and cardiovascular health, disease progression, and treatment responses in individuals with Type 1 Diabetes (T1D). It aims to support clinically relevant, mechanism-focused research that bridges sleep/circadian biology, T1D, and cardiovascular disease. Multi-disciplinary teams are strongly encouraged to apply. The ultimate goal is to develop and apply sleep and circadian strategies to enhance treatment outcomes for T1D patients and to reduce associated cardiovascular complications. Research should specifically focus on clinical investigations, excluding observational studies, epidemiology, efficacy trials, and basic animal research.
Opportunity ID: 349482
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-HL-24-008 |
| Funding Opportunity Title: | The Role of Sleep Deficiency in Persons with Type 1 Diabetes: Sleep, Glycemic Control, and Cardiovascular Risk (R01 Clinical Trial Optional) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.233 — National Center on Sleep Disorders Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Jul 20, 2023 |
| Last Updated Date: | Jul 20, 2023 |
| Original Closing Date for Applications: | Oct 11, 2023 |
| Current Closing Date for Applications: | Oct 11, 2023 |
| Archive Date: | Nov 16, 2023 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | $420,000 |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Special district governments Public and State controlled institutions of higher education County governments Native American tribal organizations (other than Federally recognized tribal governments) For profit organizations other than small businesses Native American tribal governments (Federally recognized) Private institutions of higher education State governments Independent school districts Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education City or township governments Small businesses Others (see text field entitled “Additional Information on Eligibility” for clarification) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Public housing authorities/Indian housing authorities |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | The purpose of this NOFO is to elucidate the contribution of sleep deficiency and circadian disruption to metabolic and cardiovascular pathobiology, disease trajectory, and treatment response in individuals living with Type 1 Diabetes (T1D). The RFA will support clinically relevant, mechanism focused research on the interface between sleep, circadian rhythms biology, T1D and cardiovascular disease. Multi-disciplinary teams bridging sleep/circadian, diabetes, and cardiovascular research are encouraged. Proposed research should be relevant to the ultimate goal of applying sleep and circadian strategies to improve treatment and outcomes in individuals with T1D, and to mitigate related cardiovascular complications. Observational studies, epidemiology, efficacy trials and basic animal research will not be responsive to this NOFO. |
| Link to Additional Information: | https://grants.nih.gov/grants/guide/rfa-files/RFA-HL-24-008.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH Grants Information
grantsinfo@nih.gov Email:grantsinfo@nih.gov |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
Folder 349482 Full Announcement-RFA-HL-24-008 -> RFA-HL-24-008-Full-Announcement.pdf
Packages
| Agency Contact Information: | NIH Grants Information grantsinfo@nih.gov Email: grantsinfo@nih.gov |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-H | Use for due dates on or after January 25, 2023 | PKG00282630 | Sep 11, 2023 | Oct 11, 2023 | View |
Package 1
Mandatory forms
349482 RR_SF424_5_0-5.0.pdf
349482 PHS398_CoverPageSupplement_5_0-5.0.pdf
349482 RR_OtherProjectInfo_1_4-1.4.pdf
349482 PerformanceSite_4_0-4.0.pdf
349482 RR_KeyPersonExpanded_4_0-4.0.pdf
349482 PHS398_ResearchPlan_5_0-5.0.pdf
349482 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
349482 RR_Budget_3_0-3.0.pdf
349482 RR_SubawardBudget30_3_0-3.0.pdf
349482 PHS398_ModularBudget_1_2-1.2.pdf
349482 PHS_AssignmentRequestForm_3_0-3.0.pdf
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