The National Institute on Aging (NIA) is offering this grant for pharmacokinetic and pharmacodynamic (PK/PD) studies of mTOR inhibitors. The research targets individuals with aging-related diseases or healthy older adults at risk for various aging conditions. Projects will receive individual awards but must function as a collaborative network. This network will facilitate information exchange, help develop harmonized measures, and enable data pooling. The primary goal is to broadly assess the effects of mTOR modulation on multiple aging-related outcomes and mechanisms, contributing vital insights into therapeutic strategies for aging populations.
Opportunity ID: 349560
General Information
Document Type: | Grants Notice |
Funding Opportunity Number: | RFA-AG-24-044 |
Funding Opportunity Title: | Pharmacokinetic and Pharmacodynamic (PK/PD) Studies of mTOR Inhibitors on Aging-Related Indications (U01 Clinical Trial Required) |
Opportunity Category: | Discretionary |
Opportunity Category Explanation: | – |
Funding Instrument Type: | Cooperative Agreement |
Category of Funding Activity: | Health |
Category Explanation: | – |
Expected Number of Awards: | – |
Assistance Listings: | 93.866 — Aging Research |
Cost Sharing or Matching Requirement: | No |
Version: | Synopsis 1 |
Posted Date: | Jul 26, 2023 |
Last Updated Date: | Jul 26, 2023 |
Original Closing Date for Applications: | Nov 07, 2023 |
Current Closing Date for Applications: | Nov 07, 2023 |
Archive Date: | Dec 13, 2023 |
Estimated Total Program Funding: | – |
Award Ceiling: | – |
Award Floor: | – |
Eligibility
Eligible Applicants: | Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education For profit organizations other than small businesses Small businesses Private institutions of higher education State governments Independent school districts Public housing authorities/Indian housing authorities City or township governments County governments Special district governments Public and State controlled institutions of higher education Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments) Native American tribal governments (Federally recognized) Others (see text field entitled “Additional Information on Eligibility” for clarification) |
Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed. |
Additional Information
Agency Name: | National Institutes of Health |
Description: | This Notice of Funding Opportunity (NOFO) invites applications for pharmacokinetic and pharmacodynamic (PK/PD) studies of mTOR inhibitors inpopulations living with different aging-related diseases or in relatively healthy older adult populations at risk for a variety of aging conditions. The studies will be funded by individual awards but will be required to interact as a network to exchange information, possibly develop harmonized measures, and pool data to facilitate broader assessment of the effects on multiple aging-related outcomes and mechanisms affected by mTOR modulation. |
Link to Additional Information: | https://grants.nih.gov/grants/guide/rfa-files/RFA-AG-24-044.html |
Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH Grants Information
grantsinfo@nih.gov Email:grantsinfo@nih.gov |
Version History
Version | Modification Description | Updated Date |
---|---|---|
Related Documents
Folder 349560 Full Announcement-RFA-AG-24-044 -> RFA-AG-24-044-Full-Announcement.pdf
Packages
Agency Contact Information: | NIH Grants Information grantsinfo@nih.gov Email: grantsinfo@nih.gov |
Who Can Apply: | Organization Applicants |
Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
---|---|---|---|---|---|---|
FORMS-H | Use for due dates on or after January 25, 2023 | PKG00282673 | Oct 06, 2023 | Nov 07, 2023 | View |
Package 1
Mandatory forms
349560 RR_SF424_5_0-5.0.pdf
349560 PHS398_CoverPageSupplement_5_0-5.0.pdf
349560 RR_OtherProjectInfo_1_4-1.4.pdf
349560 PerformanceSite_4_0-4.0.pdf
349560 RR_KeyPersonExpanded_4_0-4.0.pdf
349560 PHS398_ResearchPlan_5_0-5.0.pdf
349560 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
349560 RR_Budget_3_0-3.0.pdf
349560 RR_SubawardBudget30_3_0-3.0.pdf
349560 PHS398_ModularBudget_1_2-1.2.pdf
349560 PHS_AssignmentRequestForm_3_0-3.0.pdf