This grant, offered by the Health Research Department, aims to fund human studies focused on understanding the diverse physiological and functional responses to exercise training in older adults. The primary purpose is to identify the underlying factors, including systemic modulators, biomarkers, and other potential mechanisms, that contribute to this observed variability. Applicants are encouraged to propose transdisciplinary research utilizing innovative design methods, analytical approaches, and comprehensive clinical phenotyping. This approach will help disentangle the complicated relationships between endogenous and exogenous factors driving exercise response variation. Elucidating these modifiable factors and mechanisms is crucial for enabling more precise and efficacious exercise prescriptions, thereby optimizing the clinical efficacy of exercise training for older individuals.
Opportunity ID: 349809
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-AG-24-045 |
| Funding Opportunity Title: | Elucidating Variability of Physiologic and Functional Responses to Exercise Training in Older Adults (R01 Clinical Trial Required) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.866 — Aging Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Aug 09, 2023 |
| Last Updated Date: | Aug 09, 2023 |
| Original Closing Date for Applications: | Nov 03, 2023 |
| Current Closing Date for Applications: | Nov 03, 2023 |
| Archive Date: | Dec 09, 2023 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | $1,000,000 |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Independent school districts Public and State controlled institutions of higher education Others (see text field entitled “Additional Information on Eligibility” for clarification) Native American tribal organizations (other than Federally recognized tribal governments) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education State governments Special district governments City or township governments Native American tribal governments (Federally recognized) County governments Private institutions of higher education Small businesses Public housing authorities/Indian housing authorities For profit organizations other than small businesses |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | This Notice of Funding Opportunity (NOFO) invites applications to proposehuman studies to better understand thefactors underlying the response variability to exercise training in older adults. This NOFO encourages studies to identify systemic modulators, biomarkers, and other potential mechanisms underlying exercise variation in endpoints that are clinically relevant for older adults. This NOFO also encourages transdisciplinary studies utilizing innovative design methods and analytical approaches combined with clinical phenotyping to disentangle the complicated relationships between endogenous and exogenous factors that drive response variation to exercise. Elucidating factors and mechanisms that underlie variations in exercise response and the extent to which these factors are modifiable may enable more precise and efficacious exercise prescriptions to optimize the clinical efficacy of exercise training in older adults. |
| Link to Additional Information: | https://grants.nih.gov/grants/guide/rfa-files/RFA-AG-24-045.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH Grants Information
grantsinfo@nih.gov Email:grantsinfo@nih.gov |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
Folder 349809 Full Announcement-RFA-AG-24-045 -> RFA-AG-24-045-Full-Announcement.pdf
Packages
| Agency Contact Information: | NIH Grants Information grantsinfo@nih.gov Email: grantsinfo@nih.gov |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-H | Use for due dates on or after January 25, 2023 | PKG00282813 | Oct 03, 2023 | Nov 03, 2023 | View |
Package 1
Mandatory forms
349809 RR_SF424_5_0-5.0.pdf
349809 PHS398_CoverPageSupplement_5_0-5.0.pdf
349809 RR_OtherProjectInfo_1_4-1.4.pdf
349809 PerformanceSite_4_0-4.0.pdf
349809 RR_KeyPersonExpanded_4_0-4.0.pdf
349809 PHS398_ResearchPlan_5_0-5.0.pdf
349809 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
349809 RR_Budget_3_0-3.0.pdf
349809 RR_SubawardBudget30_3_0-3.0.pdf
349809 PHS398_ModularBudget_1_2-1.2.pdf
349809 PHS_AssignmentRequestForm_3_0-3.0.pdf
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