This grant is for continuing the vital work of the Childhood Liver Disease Research Network (ChiLDReN), a collaborative effort dedicated to advancing clinical and translational research on rare pediatric liver diseases. Specifically, it aims to sustain the ChiLDReN Clinical Centers, which, alongside a Scientific and Data Coordination Center, form a comprehensive network. The research encompasses a range of critical conditions affecting children, including Biliary Atresia, Alagille syndrome, alpha-1-antitrypsin deficiency, Progressive Familial Intrahepatic Cholestasis syndromes, bile acid synthesis defects, mitochondrial hepatopathies, Idiopathic Neonatal Hepatitis, Cystic Fibrosis Liver Disease, and primary sclerosing cholangitis. This funding ensures ongoing investigation into the causes, progression, and treatment of these complex liver disorders in pediatric populations, fostering improved outcomes for affected children.
Opportunity ID: 350139
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-DK-23-017 |
| Funding Opportunity Title: | Continuation of the Childhood Liver Disease Research Network (ChiLDReN) Clinical Centers (U01 Clinical Trial Required) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Cooperative Agreement |
| Category of Funding Activity: | Food and Nutrition Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.847 — Diabetes, Digestive, and Kidney Diseases Extramural Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Sep 07, 2023 |
| Last Updated Date: | Sep 07, 2023 |
| Original Closing Date for Applications: | Nov 08, 2023 |
| Current Closing Date for Applications: | Nov 08, 2023 |
| Archive Date: | Dec 14, 2023 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Others (see text field entitled “Additional Information on Eligibility” for clarification) Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments) Native American tribal governments (Federally recognized) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Special district governments Public and State controlled institutions of higher education Public housing authorities/Indian housing authorities Small businesses State governments Independent school districts City or township governments Private institutions of higher education For profit organizations other than small businesses County governments |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | The purpose of this funding opportunity announcement (FOA) is to continue the support the Childhood Liver Disease Research Network (ChiLDReN) to conduct clinical and translational research on rare pediatric liver diseases. ChiLDReN is composed of a Scientific and Data Coordination Center (SDCC) and Clinical Centers (CC). ChiLDReN will continue clinical and translational research on pediatric liver diseases that include: Biliary Atresia; Alagille syndrome; alpha-1-antitrypsin deficiency; Progressive Familial Intrahepatic Cholestasis syndromes; Bile acid synthesis defects; Mitochondrial hepatopathies; Idiopathic Neonatal Hepatitis; Cystic Fibrosis Liver Disease; and primary sclerosing cholangitis. |
| Link to Additional Information: | https://grants.nih.gov/grants/guide/rfa-files/RFA-DK-23-017.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH Grants Information
grantsinfo@nih.gov Email:grantsinfo@nih.gov |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
Folder 350139 Full Announcement-RFA-DK-23-017 -> RFA-DK-23-017-Full-Announcement.pdf
Packages
| Agency Contact Information: | NIH Grants Information grantsinfo@nih.gov Email: grantsinfo@nih.gov |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-H | Use for due dates on or after January 25, 2023 | PKG00283094 | Oct 08, 2023 | Nov 08, 2023 | View |
Package 1
Mandatory forms
350139 RR_SF424_5_0-5.0.pdf
350139 PHS398_CoverPageSupplement_5_0-5.0.pdf
350139 RR_OtherProjectInfo_1_4-1.4.pdf
350139 PerformanceSite_4_0-4.0.pdf
350139 RR_KeyPersonExpanded_4_0-4.0.pdf
350139 PHS398_ResearchPlan_5_0-5.0.pdf
350139 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
350139 RR_Budget_3_0-3.0.pdf
350139 RR_SubawardBudget30_3_0-3.0.pdf
350139 PHS398_ModularBudget_1_2-1.2.pdf
350139 PHS_AssignmentRequestForm_3_0-3.0.pdf
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