This grant is for the purpose of elucidating neurobiological mechanisms. It supports basic science experiments with humans (BESH) focused on how psychosocial stress influences neurobehavioral function and the risk for substance use disorders (SUD) and co-occurring psychiatric disorders in people living with HIV (PLWH). BESH involve prospective experimental manipulation in humans to understand fundamental processes. This opportunity targets human experimental designs; proposals using animal models or observational studies should utilize a companion grant. A mandatory Plan for Enhancing Diverse Perspectives (PEDP) is required, assessed during review, and its absence will lead to withdrawal.
Opportunity ID: 350360
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-DA-24-006 |
| Funding Opportunity Title: | Mechanistic Studies of the Effects of Psychosocial Stress on Complex Morbidity Involving SUD, Psychiatric Disorders, and HIV (R01 Basic Experimental Studies with Humans (BESH) Required) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Education Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.279 — Drug Abuse and Addiction Research Programs |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Sep 27, 2023 |
| Last Updated Date: | Sep 27, 2023 |
| Original Closing Date for Applications: | Feb 15, 2024 |
| Current Closing Date for Applications: | Feb 15, 2024 |
| Archive Date: | Mar 22, 2024 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | $500,000 |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | For profit organizations other than small businesses Public and State controlled institutions of higher education Others (see text field entitled “Additional Information on Eligibility” for clarification) County governments Private institutions of higher education State governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Public housing authorities/Indian housing authorities City or township governments Native American tribal governments (Federally recognized) Native American tribal organizations (other than Federally recognized tribal governments) Special district governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Independent school districts Small businesses |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | The purpose of this notice of funding opportunity (NOFO) is to solicit proposals for basic science experiments involving humans (BESH) aimed at elucidating neurobiological mechanisms underlying the influence of psychosocial stress on neurobehavioral function and risk for substance use disorders (SUD) and co-occurring psychiatric disorders in people living with HIV (PLWH). As referred to in NOT-OD-18-212, BESH are prospective basic science studies involving human participants that fall within the NIH definition of a clinical trial and also meet the definition of basic research. Such studies prospectively assign human participants to conditions (i.e., experimentally manipulate independent variables) and assess biomedical or behavioral outcomes in humans for the purpose of understanding the fundamental processes or principles. Applicants proposing projects involving animal models or observational studies in humans should use the companion NOFO, RFA-DA-24-005. This NOFO requires a Plan for Enhancing Diverse Perspectives (PEDP), which will be assessed as part of the scientific and technical peer review evaluation. Applications that fail to include a PEDP will be considered incomplete and will be withdrawn. Applicants are strongly encouraged to read the NOFO instructions carefully and view the available PEDP guidance material (https://extramural-intranet.nih.gov/sites/default/files/IC-Specific%20NOFO%20PEDP%20Inclusion%20Template%2003-28-2023.pdf ). |
| Link to Additional Information: | https://grants.nih.gov/grants/guide/rfa-files/RFA-DA-24-006.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH Grants Information
grantsinfo@nih.gov Email:grantsinfo@nih.gov |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
Folder 350360 Full Announcement-RFA-DA-24-006 -> RFA-DA-24-006-Full-Announcement.pdf
Packages
| Agency Contact Information: | NIH Grants Information grantsinfo@nih.gov Email: grantsinfo@nih.gov |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-H | Use for due dates on or after January 25, 2023 | PKG00283272 | Jan 15, 2024 | Feb 15, 2024 | View |
Package 1
Mandatory forms
350360 RR_SF424_5_0-5.0.pdf
350360 PHS398_CoverPageSupplement_5_0-5.0.pdf
350360 RR_OtherProjectInfo_1_4-1.4.pdf
350360 PerformanceSite_4_0-4.0.pdf
350360 RR_KeyPersonExpanded_4_0-4.0.pdf
350360 PHS398_ResearchPlan_5_0-5.0.pdf
350360 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
350360 RR_Budget_3_0-3.0.pdf
350360 RR_SubawardBudget30_3_0-3.0.pdf
350360 PHS398_ModularBudget_1_2-1.2.pdf
350360 PHS_AssignmentRequestForm_3_0-3.0.pdf
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