This grant, offered by the CounterACT program, aims to establish Research Centers of Excellence (U54s) to develop new and improved therapeutics against chemical threats. These threats include chemical warfare agents and toxic industrial chemicals. The grant supports research from target identification and characterization through candidate optimization, in vivo efficacy demonstration, and potentially Investigational New Drug (IND) submission and Phase 1 clinical trials. Each center must comprise an administrative core, scientifically related research and development subprojects, and justified scientific cores, fostering a synergistic environment. Applicants need to include progressive translational study plans with clear milestones. This U54 Cooperative Agreement seeks to advance critical countermeasures with an average of $6 million committed annually for Fiscal Years 2011-2013.
Opportunity ID: 54149
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | PAR-10-181 |
| Funding Opportunity Title: | Countermeasures Against Chemical Threats (CounterACT) Research Centers of Excellence (U54) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Cooperative Agreement |
| Category of Funding Activity: | Environment Health Income Security and Social Services |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.113 — Environmental Health |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Apr 29, 2010 |
| Last Updated Date: | – |
| Original Closing Date for Applications: | Sep 14, 2012 |
| Current Closing Date for Applications: | Sep 14, 2012 |
| Archive Date: | Oct 15, 2012 |
| Estimated Total Program Funding: | $6,000,000 |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | For profit organizations other than small businesses Private institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments) Small businesses City or township governments Special district governments Public and State controlled institutions of higher education Independent school districts Public housing authorities/Indian housing authorities Native American tribal governments (Federally recognized) Others (see text field entitled “Additional Information on Eligibility” for clarification) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education State governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education County governments |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | Purpose. This Funding Opportunity Announcement (FOA) encourages grant applications for Countermeasures Against Chemical Threats (CounterACT) Research Centers of Excellence (U54s). The mission of the CounterACT U54 program is to develop new and improved therapeutics for chemical threats. Chemical threats are toxic chemicals that could be used in a terrorist attack or accidentally released from industrial production, storage or shipping. They include traditional chemical warfare nerve agents such as sarin and VX, and toxic industrial chemicals and pesticides such as cyanide, chlorine, parathion, and sodium fluoroacetate. The scope of the research to be supported includes target and candidate identification and characterization, through candidate optimization and demonstration of in vivo efficacy, through Investigational New Drug (IND) submission and Phase 1 clinical trials when appropriate. Each new CounterACT Research Center of Excellence will be composed of an administrative core, scientifically related research and development subprojects, and scientific cores if needed and justified. Applicants must demonstrate that the formation of an interdisciplinary Center will produce a synergistic research environment that allows each project to share the creative strengths and resources of the others. Research and development plans must include milestones that create discrete go or no-go decision points in a progressive translational study plan.
Mechanism of Support. This FOA will utilize the Specialized Center Cooperative Agreement (U54) grant mechanism and runs in parallel with a FOA of identical scientific scope, PAR-10-180 that encourages applications under the Research Project Cooperative Agreements (U01) program. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/pa-files/PAR-10-181.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV Email:FBOWebmaster@OD.NIH.GOV |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
There are no related documents on this grant.
Packages
There are no packages on this grant.
Share This Post, Choose Your Platform!
About the Author: osnqt
