This grant is for advancing research into the pivotal role of adaptive immunity in the etiology of Alzheimer’s disease (AD) and Alzheimer’s disease-related dementias (AD/ADRD). The primary purpose of this funding opportunity is to foster a comprehensive understanding of brain immune surveillance mechanisms and the generation of central nervous system (CNS)-directed immune responses within neurodegenerative disorders. Specifically, it aims to delineate the functional involvement of adaptive immunity in both the onset and progression of AD/ADRD. This initiative seeks to uncover fundamental insights into how the immune system contributes to these conditions, paving the way for potential diagnostic and therapeutic breakthroughs.
Opportunity ID: 334197
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-AG-22-017 |
| Funding Opportunity Title: | Role of Adaptive Immunity in Etiology of Alzheimers Disease and Alzheimers Disease-Related Dementias (R01 Clinical Trial Optional) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.853 — Extramural Research Programs in the Neurosciences and Neurological Disorders |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Jun 16, 2021 |
| Last Updated Date: | Jun 16, 2021 |
| Original Closing Date for Applications: | Oct 28, 2021 |
| Current Closing Date for Applications: | Oct 28, 2021 |
| Archive Date: | Dec 03, 2021 |
| Estimated Total Program Funding: | $8,000,000 |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Public and State controlled institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments) Special district governments Independent school districts Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education State governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education For profit organizations other than small businesses Private institutions of higher education Others (see text field entitled “Additional Information on Eligibility” for clarification) County governments City or township governments Native American tribal governments (Federally recognized) Public housing authorities/Indian housing authorities Small businesses |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | This Funding Opportunity Announcement (FOA) aims to explore the role of adaptive immunity in Alzheimers disease and Alzheimers disease-related dementias (AD/ADRD). Specifically, the FOA seeks an understanding of brain immune surveillance, the generation of CNS-directed immune responses in neurodegenerative disorders, and the functional role of adaptive immunity in AD/ADRD onset and progression. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/rfa-files/RFA-AG-22-017.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
grantsinfo@nih.gov Email:grantsinfo@nih.gov |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
There are no related documents on this grant.
Packages
| Agency Contact Information: | NIH OER Webmaster grantsinfo@nih.gov Email: grantsinfo@nih.gov |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-F | Use for due dates on or before January 24, 2022 | PKG00267781 | Sep 28, 2021 | Jan 24, 2022 | View |
Package 1
Mandatory forms
334197 RR_SF424_2_0-2.0.pdf
334197 PHS398_CoverPageSupplement_5_0-5.0.pdf
334197 RR_OtherProjectInfo_1_4-1.4.pdf
334197 PerformanceSite_2_0-2.0.pdf
334197 RR_KeyPersonExpanded_2_0-2.0.pdf
334197 PHS398_ResearchPlan_4_0-4.0.pdf
334197 PHSHumanSubjectsAndClinicalTrialsInfo_2_0-2.0.pdf
Optional forms
334197 RR_Budget_1_4-1.4.pdf
334197 RR_SubawardBudget30_1_4-1.4.pdf
334197 PHS398_ModularBudget_1_2-1.2.pdf
334197 PHS_AssignmentRequestForm_3_0-3.0.pdf
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