The National Cancer Institute (NCI) is offering this grant opportunity to establish Precancer Atlas (PCA) Research Centers. This grant is for constructing comprehensive three-dimensional (3D) and dynamic atlases of human precancerous lesions and their microenvironments. The core purpose is to understand the transition from these lesions to malignancy. Each PCA Research Center will develop a 3D precancer atlas, meticulously characterizing cellular, molecular, and spatial features of pre-malignant states. These centers are a key component of the Human Tumor Atlas Network (HTAN), a collaborative initiative dedicated to mapping the progression of human cancers from precancerous lesions to advanced disease.
Opportunity ID: 350463
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-CA-23-040 |
| Funding Opportunity Title: | Pre-Cancer Atlas (PCA) Research Centers (U01 Clinical Trial Not Allowed) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Cooperative Agreement |
| Category of Funding Activity: | Education Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.393 — Cancer Cause and Prevention Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Oct 04, 2023 |
| Last Updated Date: | Oct 04, 2023 |
| Original Closing Date for Applications: | Dec 05, 2023 |
| Current Closing Date for Applications: | Dec 05, 2023 |
| Archive Date: | Jan 10, 2024 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | $800,000 |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | County governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education City or township governments Others (see text field entitled “Additional Information on Eligibility” for clarification) State governments Private institutions of higher education Native American tribal governments (Federally recognized) Small businesses Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Special district governments Native American tribal organizations (other than Federally recognized tribal governments) For profit organizations other than small businesses Public housing authorities/Indian housing authorities Independent school districts Public and State controlled institutions of higher education |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | The purpose of this Notice of Funding Opportunity (NOFO) is to solicit applications for Precancer Atlas (PCA) Research Centers, one of the three scientific components of the Human Tumor Atlas Network (HTAN) (https://humantumoratlas.org/).HTAN is a collaborative research initiative for constructing 3-dimensional(3D) and dynamic atlases of the cellular, morphological, molecular, and spatial features of human cancers and their surrounding microenvironments as they progress from precancerous lesions to advanced disease.Each PCA Research Center will construct one 3D precancer atlas that comprehensively characterizes a pre-malignant lesion with an explicit focus on understanding the transition from a precancerous lesion to malignancy. The other two HTAN components are Human Tumor Atlas (HTA) Research Centers and a Data Coordinating Center (DCC).Each HTA Research Center will conduct research to develop onespatial tumor atlas at single-cell resolution driven by specific topics in cancer biology across the continuum from cancer initiation to metastasis. |
| Link to Additional Information: | https://grants.nih.gov/grants/guide/rfa-files/RFA-CA-23-040.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH Grants Information
grantsinfo@nih.gov Email:grantsinfo@nih.gov |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
Folder 350463 Full Announcement-RFA-CA-23-040 -> RFA-CA-23-040-Full-Announcement.pdf
Packages
| Agency Contact Information: | NIH Grants Information grantsinfo@nih.gov Email: grantsinfo@nih.gov |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-H | Use for due dates on or after January 25, 2023 | PKG00283362 | Nov 05, 2023 | Dec 05, 2023 | View |
Package 1
Mandatory forms
350463 RR_SF424_5_0-5.0.pdf
350463 PHS398_CoverPageSupplement_5_0-5.0.pdf
350463 RR_OtherProjectInfo_1_4-1.4.pdf
350463 PerformanceSite_4_0-4.0.pdf
350463 RR_KeyPersonExpanded_4_0-4.0.pdf
350463 PHS398_ResearchPlan_5_0-5.0.pdf
350463 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
350463 RR_Budget_3_0-3.0.pdf
350463 RR_SubawardBudget30_3_0-3.0.pdf
350463 PHS398_ModularBudget_1_2-1.2.pdf
350463 PHS_AssignmentRequestForm_3_0-3.0.pdf
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