The National Institute on Deafness and Other Communication Disorders (NIDCD) is offering this grant to encourage research into the development, characterization, and reproducibility of human auditory and vestibular organoids. This grant is for advancing innovative and reproducible methodologies that enhance the longevity and stability of these organoids as robust model systems. Proposals are highly encouraged for novel tools that facilitate gene, protein, or molecule delivery to achieve successful expansion and long-term survivability of organoid populations. The subsequent characterization of these platforms must demonstrate mimicry of native biological function. The NIDCD seeks breakthrough approaches that overcome current barriers, improving reproducibility and stability in human auditory/vestibular organoid research.
Opportunity ID: 350714
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | PAS-24-057 |
| Funding Opportunity Title: | Advancing Hearing and Balance Research Using Auditory and Vestibular Organoids (R21-Clinical Trial Not Allowed) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.173 — Research Related to Deafness and Communication Disorders |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Oct 25, 2023 |
| Last Updated Date: | Oct 25, 2023 |
| Original Closing Date for Applications: | May 07, 2024 |
| Current Closing Date for Applications: | May 07, 2024 |
| Archive Date: | Jun 12, 2024 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | $275,000 |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Independent school districts City or township governments Private institutions of higher education State governments Public and State controlled institutions of higher education For profit organizations other than small businesses Special district governments Small businesses County governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments) Public housing authorities/Indian housing authorities Native American tribal governments (Federally recognized) Others (see text field entitled “Additional Information on Eligibility” for clarification) |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | The purpose of this NIDCD initiative is to encourage research in the development, characterization, and reproducibility/reliability of human auditory and vestibular organoids. Proposals investigating animal organoids are allowable but only if accompanying comparative or other integrated companion studies with human organoids. Singular animal organoid studies alone are not responsive to this funding opportunity. This funding opportunity encourages innovative, reproducible, and novel methodologies and technologies that will drive the reproducibility and holistic longevity of hearing/balance sensory organoids as model systems. The development of novel tools to deliver genes, proteins, molecules, and synthetics that might lead to the successful expansion and longer-term survivability of organoid populations in a stable, reliable, and reproducible manner is highly encouraged. Subsequent characterization of the organoid platforms must be shown to mimic and recapitulate the native correlative biological function. Applications that provide approaches that remove current barriers and lessen challenges to improve current reproducibility and stability are highly encouraged. Applications that have breakthrough approaches and technologies using human auditory/vestibular organoids are highly encouraged. |
| Link to Additional Information: | https://grants.nih.gov/grants/guide/pa-files/PAS-24-057.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH Grants Information
grantsinfo@nih.gov Email:grantsinfo@nih.gov |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
Folder 350714 Full Announcement-PAS-24-057 -> PAS-24-057-Full-Announcement.pdf
Packages
| Agency Contact Information: | NIH Grants Information grantsinfo@nih.gov Email: grantsinfo@nih.gov |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-H | Use for due dates on or after January 25, 2023 | PKG00283597 | Jan 16, 2024 | May 07, 2024 | View |
Package 1
Mandatory forms
350714 RR_SF424_5_0-5.0.pdf
350714 PHS398_CoverPageSupplement_5_0-5.0.pdf
350714 RR_OtherProjectInfo_1_4-1.4.pdf
350714 PerformanceSite_4_0-4.0.pdf
350714 RR_KeyPersonExpanded_4_0-4.0.pdf
350714 PHS398_ResearchPlan_5_0-5.0.pdf
350714 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
350714 RR_Budget_3_0-3.0.pdf
350714 RR_SubawardBudget30_3_0-3.0.pdf
350714 PHS398_ModularBudget_1_2-1.2.pdf
350714 PHS_AssignmentRequestForm_3_0-3.0.pdf
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