The National Cancer Institute (NCI) offers the Pathway to Independence Award (K99/R00) to cultivate a strong cohort of new, independent investigators. This grant is specifically designed for early-stage postdoctoral fellows with research or clinical doctoral degrees, who are ready to transition from mentored research to independent tenure-track faculty positions without extensive additional training. The NCI provides independent research support to help awardees launch competitive careers. Researchers in cancer control, prevention, and data sciences are particularly encouraged. This specific grant opportunity supports research that does not involve leading independent clinical trials, though participation in mentor-led clinical trials is permitted. Its core purpose is to facilitate the timely transition of promising postdocs into leading research roles.
Opportunity ID: 350943
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | PAR-23-286 |
| Funding Opportunity Title: | NCI Pathway to Independence Award for Early-Stage Postdoctoral Researchers (K99/R00 – Independent Clinical Trial Not Allowed) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Education Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.398 — Cancer Research Manpower |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Nov 09, 2023 |
| Last Updated Date: | Nov 09, 2023 |
| Original Closing Date for Applications: | Oct 14, 2026 |
| Current Closing Date for Applications: | Oct 14, 2026 |
| Archive Date: | Nov 19, 2026 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | State governments Independent school districts City or township governments County governments Private institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Public and State controlled institutions of higher education Others (see text field entitled “Additional Information on Eligibility” for clarification) Special district governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Small businesses Public housing authorities/Indian housing authorities Native American tribal governments (Federally recognized) For profit organizations other than small businesses Native American tribal organizations (other than Federally recognized tribal governments) |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | The purpose of the NCI Pathway to Independence Award for Early-Stage Postdoctoral Researchers (K99/R00) program is to increase and maintain a strong cohort of new and talented, NCI-supported, independent investigators. This program is designed for postdoctoral fellows with research and/or clinical doctoral degrees who do not require an extended period of mentored research training beyond their doctoral degrees. The objective of this award is to facilitate a timely transition of these fellows from their mentored, postdoctoral research positions to independent tenure-track (or equivalent) faculty positions. The program will provide independent NCI research support during this transition to help awardees to launch competitive, independent research careers. Researchers in the scientific areas of cancer control, cancer prevention and cancer data sciences are especially encouraged to work with their institutions to apply. This Notice of Funding Opportunity (NOFO) is designed specifically for candidates proposing research that does not involve leading an independent clinical trial, a clinical trial feasibility study, or an ancillary clinical trial. Under this NOFO candidates are permitted to propose a research experience in a clinical trial led by a mentor or co-mentor. Those proposing a clinical trial or an ancillary clinical trial as lead investigator, should apply to the companion NOFOs (PAR-23-287 or PAR-23-288). |
| Link to Additional Information: | https://grants.nih.gov/grants/guide/pa-files/PAR-23-286.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH Grants Information
grantsinfo@nih.gov Email:grantsinfo@nih.gov |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
Folder 350943 Full Announcement-PAR-23-286 -> PAR-23-286-Full-Announcement.pdf
Packages
| Agency Contact Information: | NIH Grants Information grantsinfo@nih.gov Email: grantsinfo@nih.gov |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-H | Use for due dates on or before January 24, 2025 | PKG00283760 | Jan 14, 2024 | Jan 24, 2025 | View | |
| FORMS-I | Use for due dates on or after January 25, 2025 | PKG00289155 | Nov 27, 2024 | Oct 14, 2026 | View |
Package 1
Mandatory forms
350943 RR_SF424_5_0-5.0.pdf
350943 PHS398_CoverPageSupplement_5_0-5.0.pdf
350943 RR_OtherProjectInfo_1_4-1.4.pdf
350943 PerformanceSite_4_0-4.0.pdf
350943 RR_KeyPersonExpanded_4_0-4.0.pdf
350943 RR_Budget10_3_0-3.0.pdf
350943 PHS398_CareerDevelopmentAwardSup_6_0-6.0.pdf
350943 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
350943 RR_SubawardBudget10_30_3_0-3.0.pdf
350943 PHS_AssignmentRequestForm_4_0-4.0.pdf
Package 2
Mandatory forms
350943 RR_SF424_5_0-5.0.pdf
350943 PHS398_CoverPageSupplement_5_0-5.0.pdf
350943 RR_OtherProjectInfo_1_4-1.4.pdf
350943 PerformanceSite_4_0-4.0.pdf
350943 RR_KeyPersonExpanded_4_0-4.0.pdf
350943 RR_Budget10_3_0-3.0.pdf
350943 PHS398_CareerDevelopmentAwardSup_6_0-6.0.pdf
350943 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
350943 RR_SubawardBudget10_30_3_0-3.0.pdf
350943 PHS_AssignmentRequestForm_3_0-3.0.pdf
Share This Post, Choose Your Platform!
About the Author: osnqt
