This NCI grant is designed to cultivate a strong cohort of new, independent investigators by facilitating the timely transition of early-stage postdoctoral fellows to tenure-track or equivalent faculty positions. It provides independent NCI research support to help awardees launch competitive careers. The program targets postdoctoral researchers with doctoral degrees who do not require extended mentored training. Researchers in cancer control, prevention, and data sciences are particularly encouraged to apply. This specific funding opportunity is for basic science experimental studies involving human participants, defined as prospective basic science studies that experimentally manipulate independent variables to understand fundamental phenomena. This award helps bridge the gap from mentored research to independent research careers within the NCI’s scientific areas.
Opportunity ID: 350945
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | PAR-23-288 |
| Funding Opportunity Title: | NCI Pathway to Independence Award for Early-Stage Postdoctoral Researchers (K99/R00 – Independent Basic Experimental Studies with Humans Required) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Education Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.398 — Cancer Research Manpower |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Nov 09, 2023 |
| Last Updated Date: | Nov 09, 2023 |
| Original Closing Date for Applications: | Oct 14, 2026 |
| Current Closing Date for Applications: | Oct 14, 2026 |
| Archive Date: | Nov 19, 2026 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Public housing authorities/Indian housing authorities State governments Public and State controlled institutions of higher education For profit organizations other than small businesses Small businesses Native American tribal governments (Federally recognized) Independent school districts Native American tribal organizations (other than Federally recognized tribal governments) County governments Others (see text field entitled “Additional Information on Eligibility” for clarification) City or township governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Special district governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Private institutions of higher education |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | The purpose of the NCI Pathway to Independence Award for Early-Stage Postdoctoral Researchers (K99/R00) program is to increase and maintain a strong cohort of new and talented, NCI-supported, independent investigators. This program is designed for postdoctoral fellows with research and/or clinical doctoral degrees who do not require an extended period of mentored research training beyond their doctoral degrees. The objective of this award is to facilitate a timely transition of these fellows from their mentored, postdoctoral research positions to independent tenure-track (or equivalent) faculty positions. The program will provide independent NCI research support during this transition to help awardees to launch competitive, independent research careers. Researchers in the scientific areas of cancer control, cancer prevention and cancer data sciences are especially encouraged to work with their institutions to apply. This notice of funding opportunity (NOFO) is for basic science experimental studies involving humans, referred to in NOT-OD-18-212 as prospective basic science studies involving human participants. These studies fall within the NIH definition of a clinical trial and also meet the definition of basic research. Types of studies that should be submitted under this NOFO include studies that prospectively assign human participants to conditions (i.e., experimentally manipulate independent variables) and that assess biomedical or behavioral outcomes in humans for the purpose of understanding the fundamental aspects of phenomena without specific application towards processes or products in mind. Those not planning an independent clinical trial or basic experimental study with humans, or proposing to gain research experience in a clinical trial or basic experimental study with humans led by another investigator, must apply to the ‘Independent Clinical Trial Not Allowed’ companion NOFO (PAR-23-286). |
| Link to Additional Information: | https://grants.nih.gov/grants/guide/pa-files/PAR-23-288.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH Grants Information
grantsinfo@nih.gov Email:grantsinfo@nih.gov |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
Folder 350945 Full Announcement-PAR-23-288 -> PAR-23-288-Full-Announcement.pdf
Packages
| Agency Contact Information: | NIH Grants Information grantsinfo@nih.gov Email: grantsinfo@nih.gov |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-H | Use for due dates on or before January 24, 2025 | PKG00283762 | Jan 14, 2024 | Jan 24, 2025 | View | |
| FORMS-I | Use for due dates on or after January 25, 2025 | PKG00289158 | Nov 27, 2024 | Oct 14, 2026 | View |
Package 1
Mandatory forms
350945 RR_SF424_5_0-5.0.pdf
350945 PHS398_CoverPageSupplement_5_0-5.0.pdf
350945 RR_OtherProjectInfo_1_4-1.4.pdf
350945 PerformanceSite_4_0-4.0.pdf
350945 RR_KeyPersonExpanded_4_0-4.0.pdf
350945 RR_Budget10_3_0-3.0.pdf
350945 PHS398_CareerDevelopmentAwardSup_6_0-6.0.pdf
350945 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
350945 RR_SubawardBudget10_30_3_0-3.0.pdf
350945 PHS_AssignmentRequestForm_4_0-4.0.pdf
Package 2
Mandatory forms
350945 RR_SF424_5_0-5.0.pdf
350945 PHS398_CoverPageSupplement_5_0-5.0.pdf
350945 RR_OtherProjectInfo_1_4-1.4.pdf
350945 PerformanceSite_4_0-4.0.pdf
350945 RR_KeyPersonExpanded_4_0-4.0.pdf
350945 RR_Budget10_3_0-3.0.pdf
350945 PHS398_CareerDevelopmentAwardSup_6_0-6.0.pdf
350945 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
350945 RR_SubawardBudget10_30_3_0-3.0.pdf
350945 PHS_AssignmentRequestForm_3_0-3.0.pdf
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