This grant aims to establish a clinical consortium focused on youth-onset Type 2 Diabetes (T2D). The initiative seeks to recruit and study a cohort of early pubertal youth at risk for T2D throughout their pubertal development. A primary objective is to enhance the precise prediction of individuals truly susceptible to youth-onset T2D and identify key factors driving progression from prediabetes. This understanding will facilitate the development and testing of targeted prevention strategies. Furthermore, the grant seeks to deepen knowledge of the physiological mechanisms underlying youth-onset T2D. This research will inform the creation of more effective interventions for achieving glycemic control and preserving vital beta cell function in affected youth.
Opportunity ID: 334716
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-DK-21-002 |
| Funding Opportunity Title: | Understanding and Targeting the Pathophysiology of Youth-onset Type 2 Diabetes Clinical Centers (U01 Clinical Trial Not Allowed) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Cooperative Agreement |
| Category of Funding Activity: | Food and Nutrition Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.847 — Diabetes, Digestive, and Kidney Diseases Extramural Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Jul 14, 2021 |
| Last Updated Date: | Jul 14, 2021 |
| Original Closing Date for Applications: | Mar 03, 2022 |
| Current Closing Date for Applications: | Mar 03, 2022 |
| Archive Date: | Apr 08, 2022 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Public and State controlled institutions of higher education Independent school districts Special district governments Private institutions of higher education Small businesses Others (see text field entitled “Additional Information on Eligibility” for clarification) City or township governments State governments For profit organizations other than small businesses Public housing authorities/Indian housing authorities Native American tribal organizations (other than Federally recognized tribal governments) County governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Native American tribal governments (Federally recognized) |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are not allowed. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | The purpose of this FOA is to ?c?r?e?a?t?e? ?a? ?c?l?i?n?i?c?a?l? consortium to recruit a cohort o?f early pubertal youth at risk for developing type 2 diabetes and study them th?r?o?ugh puberty. The ultimate goal of this undertaking will be to 1) develop more precise prediction of which individuals are truly at risk for developing you?t?h-onset T2D and identify determinants of progression from prediabetes to T2D so that, ultimately, targeted prevention approaches can be developed and tested; and 2) increase understanding ofthe physiologic drivers of youth-onset T2D to guide development of more effective strategies to achieve glycemic control and preserve beta cell function. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/rfa-files/RFA-DK-21-002.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
grantsinfo@nih.gov Email:grantsinfo@nih.gov |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
Folder 334716 Full Announcement-RFA-DK-21-002 -> RFA-DK-21-002-Full-Announcement.pdf
Packages
| Agency Contact Information: | NIH OER Webmaster grantsinfo@nih.gov Email: grantsinfo@nih.gov |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-G | Use for due dates on or after January 25, 2022 | PKG00270435 | Feb 03, 2022 | Mar 03, 2022 | View | |
| FORMS-F | Use for due dates on or before January 24, 2022 | PKG00268183 | Feb 03, 2022 | Jan 24, 2022 | View |
Package 1
Mandatory forms
334716 RR_SF424_5_0-5.0.pdf
334716 PHS398_CoverPageSupplement_5_0-5.0.pdf
334716 RR_OtherProjectInfo_1_4-1.4.pdf
334716 PerformanceSite_4_0-4.0.pdf
334716 RR_KeyPersonExpanded_4_0-4.0.pdf
334716 PHS398_ResearchPlan_4_0-4.0.pdf
334716 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
334716 RR_Budget_3_0-3.0.pdf
334716 RR_SubawardBudget30_3_0-3.0.pdf
334716 PHS398_ModularBudget_1_2-1.2.pdf
334716 PHS_AssignmentRequestForm_3_0-3.0.pdf
Package 2
Mandatory forms
334716 RR_SF424_2_0-2.0.pdf
334716 PHS398_CoverPageSupplement_5_0-5.0.pdf
334716 RR_OtherProjectInfo_1_4-1.4.pdf
334716 PerformanceSite_2_0-2.0.pdf
334716 RR_KeyPersonExpanded_2_0-2.0.pdf
334716 PHS398_ResearchPlan_4_0-4.0.pdf
334716 PHSHumanSubjectsAndClinicalTrialsInfo_2_0-2.0.pdf
Optional forms
334716 RR_Budget_1_4-1.4.pdf
334716 RR_SubawardBudget30_1_4-1.4.pdf
334716 PHS398_ModularBudget_1_2-1.2.pdf
334716 PHS_AssignmentRequestForm_3_0-3.0.pdf
Share This Post, Choose Your Platform!
About the Author: osnqt
