This grant supports pilot and preliminary research for developing effective, non-stigmatizing overdose prevention, substance use disorder (SUD) treatment, and recovery services for adolescents. The goal is to prepare for rigorous, large-scale trials expanding impactful interventions. Studies can examine changes in overdose risk behaviors, like using alone or Naloxone use. Outcomes of interest include harm reduction, recovery, treatment retention, effectiveness, quality of care, patient-centered outcomes, and implementation factors. Ultimately, this initiative aims to develop youth-focused interventions that are effective, practical, cost-effective, scalable, and sustainable.
Opportunity ID: 351038
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-DA-25-031 |
| Funding Opportunity Title: | Adolescent Overdose Prevention and SUD Treatment Initiative (R34 – Clinical Trial Optional) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Education Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.279 — Drug Abuse and Addiction Research Programs |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Nov 17, 2023 |
| Last Updated Date: | Nov 17, 2023 |
| Original Closing Date for Applications: | Mar 13, 2024 |
| Current Closing Date for Applications: | Mar 13, 2024 |
| Archive Date: | Apr 18, 2024 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Private institutions of higher education Public housing authorities/Indian housing authorities Independent school districts Others (see text field entitled “Additional Information on Eligibility” for clarification) Special district governments Native American tribal governments (Federally recognized) City or township governments Native American tribal organizations (other than Federally recognized tribal governments) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education For profit organizations other than small businesses Small businesses Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education State governments Public and State controlled institutions of higher education County governments |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | This Notice of Funding Opportunity (NOFO) encourages pilot work and preliminary research to support preparation for large-scale, rigorous trials that will guide the expansion of effective, non-stigmatizing overdose prevention, SUD treatment and recovery services for adolescents. These studies could include examining changes in risk behaviors associated with overdose (e.g., using alone, carrying/using Naloxone). Outcomes of interest include but are not limited to harm reduction, recovery, treatment retention and effectiveness, quality of care, patient-centered outcomes, and implementation factors. The goal of this NOFO is to develop interventions that address effective, non-stigmatizing overdose prevention, SUD treatment and recovery services for youth that are effective, practical, cost-effective, scalable, and sustainable. |
| Link to Additional Information: | https://grants.nih.gov/grants/guide/rfa-files/RFA-DA-25-031.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH Grants Information
grantsinfo@nih.gov Email:grantsinfo@nih.gov |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
Folder 351038 Full Announcement-RFA-DA-25-031 -> RFA-DA-25-031-Full-Announcement.pdf
Packages
| Agency Contact Information: | NIH Grants Information grantsinfo@nih.gov Email: grantsinfo@nih.gov |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-H | Use for due dates on or after January 25, 2023 | PKG00283826 | Feb 13, 2024 | Mar 13, 2024 | View |
Package 1
Mandatory forms
351038 RR_SF424_5_0-5.0.pdf
351038 PHS398_CoverPageSupplement_5_0-5.0.pdf
351038 RR_OtherProjectInfo_1_4-1.4.pdf
351038 PerformanceSite_4_0-4.0.pdf
351038 RR_KeyPersonExpanded_4_0-4.0.pdf
351038 PHS398_ResearchPlan_5_0-5.0.pdf
351038 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
351038 RR_Budget_3_0-3.0.pdf
351038 RR_SubawardBudget30_3_0-3.0.pdf
351038 PHS398_ModularBudget_1_2-1.2.pdf
351038 PHS_AssignmentRequestForm_3_0-3.0.pdf
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