This NIH SBIR Program grant is for developing Miniaturization and Automation of Tissue Chip Systems (MATChS). The initiative supports research and development of innovative tools and turnkey technologies. The focus is on achieving higher throughput automated measures, incorporating on-line sensing, and facilitating rapid data acquisition and analysis to minimize manual handling. Successful projects will significantly increase the availability of miniaturized, automated tissue chip platforms, establishing them as essential research tools in drug development and across diverse biomedical research laboratories. As a cooperative agreement, small business concerns (SBCs) are required to set clear milestones, collaborate closely with NIH staff, and demonstrate viable pathways for commercialization of their automated systems.
Opportunity ID: 351096
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-TR-23-017 |
| Funding Opportunity Title: | Miniaturization and Automation of Tissue Chip Systems (MATChS) (U43/U44 Clinical Trial Not Allowed) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Cooperative Agreement |
| Category of Funding Activity: | Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.350 — National Center for Advancing Translational Sciences |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Nov 22, 2023 |
| Last Updated Date: | Nov 22, 2023 |
| Original Closing Date for Applications: | Feb 23, 2026 |
| Current Closing Date for Applications: | Feb 23, 2026 |
| Archive Date: | Mar 31, 2026 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Small businesses |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are not allowed. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | This NOFO provides support using the SBIR cooperative agreement mechanisms for the development of MATChS. Applications considered responsive to this would include those proposing research and development of tools and turnkey technologies for higher throughput automated measures with on-line sensing, rapid acquisition and analysis of data to reduce manual handling. Funded projects will result in an increased availability of miniaturized automated tissue chip platforms for use in drug development and across multiple applications as a major research tool in biomedical research laboratories. As a cooperative agreement, small business concerns (SBCs) will be expected to develop milestones and benchmarks, and work with NIH staff towards progress in the aims of the project to develop an automated system and demonstrable pathways to commercialization. |
| Link to Additional Information: | https://grants.nih.gov/grants/guide/rfa-files/RFA-TR-23-017.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH Grants Information
grantsinfo@nih.gov Email:grantsinfo@nih.gov |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
Folder 351096 Full Announcement-RFA-TR-23-017 -> RFA-TR-23-017-Full-Announcement.pdf
Packages
| Agency Contact Information: | NIH Grants Information grantsinfo@nih.gov Email: grantsinfo@nih.gov |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-H | Use for due dates on or before January 24, 2025 | PKG00283872 | Jan 22, 2024 | Jan 24, 2025 | View | |
| FORMS-I | Use for due dates on or after January 25, 2025 | PKG00289262 | Nov 27, 2024 | Feb 23, 2026 | View |
Package 1
Mandatory forms
351096 RR_SF424_5_0-5.0.pdf
351096 PHS398_CoverPageSupplement_5_0-5.0.pdf
351096 RR_OtherProjectInfo_1_4-1.4.pdf
351096 PerformanceSite_4_0-4.0.pdf
351096 RR_KeyPersonExpanded_4_0-4.0.pdf
351096 RR_Budget_3_0-3.0.pdf
351096 PHS398_ResearchPlan_5_0-5.0.pdf
351096 SBIR_STTR_Information_3_0-3.0.pdf
351096 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
351096 RR_SubawardBudget30_3_0-3.0.pdf
351096 PHS_AssignmentRequestForm_4_0-4.0.pdf
Package 2
Mandatory forms
351096 RR_SF424_5_0-5.0.pdf
351096 PHS398_CoverPageSupplement_5_0-5.0.pdf
351096 RR_OtherProjectInfo_1_4-1.4.pdf
351096 PerformanceSite_4_0-4.0.pdf
351096 RR_KeyPersonExpanded_4_0-4.0.pdf
351096 RR_Budget_3_0-3.0.pdf
351096 PHS398_ResearchPlan_5_0-5.0.pdf
351096 SBIR_STTR_Information_3_0-3.0.pdf
351096 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
351096 RR_SubawardBudget30_3_0-3.0.pdf
351096 PHS_AssignmentRequestForm_3_0-3.0.pdf
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