This R01 grant, offered by multiple NIH Institutes, encourages applications for developing high-throughput screening (HTS) assays. Its purpose is to identify small molecule compounds that serve as probes to advance knowledge, identify new targets, or act as pre-therapeutic leads. This initiative establishes a robust pipeline of outstanding assays for NIH-supported screening centers. Proposed assays must be relevant to processes and diseases within at least one sponsoring NIH Institute’s mission, including rare and neglected diseases, providing valuable biological insights.
Opportunity ID: 55102
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | PA-10-213 |
| Funding Opportunity Title: | Development of Assays for High-Throughput screening for use in Probe and Pre-therapeutic Discovery (R01) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Education Food and Nutrition Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.233 — National Center on Sleep Disorders Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 2 |
| Posted Date: | Jun 10, 2010 |
| Last Updated Date: | Oct 14, 2010 |
| Original Closing Date for Applications: | Sep 07, 2013 |
| Current Closing Date for Applications: | Sep 07, 2013 |
| Archive Date: | Oct 08, 2013 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | City or township governments Special district governments Independent school districts Native American tribal governments (Federally recognized) Public housing authorities/Indian housing authorities Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education For profit organizations other than small businesses Small businesses Public and State controlled institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Others (see text field entitled “Additional Information on Eligibility” for clarification) State governments County governments Private institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments) |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | Purpose. This FOA issued by the NIDDK, NCI, NHLBI, NIA, NIAAA, NIAID, NIDR, NIGMS and NIMH of the National Institutes of Health,encourages Research Project Grant (R01) applications from institutions/organizations that propose the development of assays for high throughput screening (HTS) relevant to processes and diseases specific to its mission with the intent of using them to screen for small molecule compounds that show desired properties as probes for use in advancing knowledge about the relevant target, identifying new targets, or serving as pre-therapeutic leads. The NIH launched a Molecular Libraries and Imaging initiative as part of the NIH Roadmap for Medical Research to establish a network of HTS screening centers which provide access to a large compound library, robotics to carry out the assays, and informatics to interpret the results (http://mli.nih.gov/mli/). This FOA seeks to establish a stream of scientifically and technologically outstanding assays for screening by these and other academic centers. Assays may involve targets indirectly related to disease, but which might provide insight into the biology of relevant diseases. Other targets might be associated with rare and neglected diseases, an area of increasing focus for the NIH (http://www.nih.gov/news/health/may2009/nhgri-20.htm). Assays should be relevant to the scope of the research for at least one of the sponsoring NIH Institutes. Mechanism of Support. This FOA will utilize the R01 grant mechanism. Funds Available and Anticipated Number of Awards. Because the nature and scope of the proposed research will vary from application to application, it is anticipated that the size and duration of each award will also vary. The total amount awarded and the number of awards will depend upon the mechanism numbers, quality, duration, and costs of the applications received. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/pa-files/PA-10-213.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV Email:FBOWebmaster@OD.NIH.GOV |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
| Updated to remove invalid CFDA No. 93.272. | Oct 14, 2010 | |
| Oct 14, 2010 |
DISPLAYING: Synopsis 2
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | PA-10-213 |
| Funding Opportunity Title: | Development of Assays for High-Throughput screening for use in Probe and Pre-therapeutic Discovery (R01) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Education Food and Nutrition Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.233 — National Center on Sleep Disorders Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 2 |
| Posted Date: | Jun 10, 2010 |
| Last Updated Date: | Oct 14, 2010 |
| Original Closing Date for Applications: | Sep 07, 2013 |
| Current Closing Date for Applications: | Sep 07, 2013 |
| Archive Date: | Oct 08, 2013 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | City or township governments Special district governments Independent school districts Native American tribal governments (Federally recognized) Public housing authorities/Indian housing authorities Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education For profit organizations other than small businesses Small businesses Public and State controlled institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Others (see text field entitled “Additional Information on Eligibility” for clarification) State governments County governments Private institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments) |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | Purpose. This FOA issued by the NIDDK, NCI, NHLBI, NIA, NIAAA, NIAID, NIDR, NIGMS and NIMH of the National Institutes of Health,encourages Research Project Grant (R01) applications from institutions/organizations that propose the development of assays for high throughput screening (HTS) relevant to processes and diseases specific to its mission with the intent of using them to screen for small molecule compounds that show desired properties as probes for use in advancing knowledge about the relevant target, identifying new targets, or serving as pre-therapeutic leads. The NIH launched a Molecular Libraries and Imaging initiative as part of the NIH Roadmap for Medical Research to establish a network of HTS screening centers which provide access to a large compound library, robotics to carry out the assays, and informatics to interpret the results (http://mli.nih.gov/mli/). This FOA seeks to establish a stream of scientifically and technologically outstanding assays for screening by these and other academic centers. Assays may involve targets indirectly related to disease, but which might provide insight into the biology of relevant diseases. Other targets might be associated with rare and neglected diseases, an area of increasing focus for the NIH (http://www.nih.gov/news/health/may2009/nhgri-20.htm). Assays should be relevant to the scope of the research for at least one of the sponsoring NIH Institutes. Mechanism of Support. This FOA will utilize the R01 grant mechanism. Funds Available and Anticipated Number of Awards. Because the nature and scope of the proposed research will vary from application to application, it is anticipated that the size and duration of each award will also vary. The total amount awarded and the number of awards will depend upon the mechanism numbers, quality, duration, and costs of the applications received. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/pa-files/PA-10-213.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV Email:FBOWebmaster@OD.NIH.GOV |
DISPLAYING: Synopsis 1
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | PA-10-213 |
| Funding Opportunity Title: | Development of Assays for High-Throughput screening for use in Probe and Pre-therapeutic Discovery (R01) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Education Food and Nutrition Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.233 — National Center on Sleep Disorders Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Oct 14, 2010 |
| Last Updated Date: | – |
| Original Closing Date for Applications: | – |
| Current Closing Date for Applications: | Sep 07, 2013 |
| Archive Date: | Oct 08, 2013 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Others (see text field entitled “Additional Information on Eligibility” for clarification) Native American tribal governments (Federally recognized) Public and State controlled institutions of higher education Public housing authorities/Indian housing authorities Private institutions of higher education State governments Special district governments Independent school districts County governments City or township governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Small businesses Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments) For profit organizations other than small businesses |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | Purpose. This FOA issued by the NIDDK, NCI, NHLBI, NIA, NIAAA, NIAID, NIDR, NIGMS and NIMH of the National Institutes of Health,encourages Research Project Grant (R01) applications from institutions/organizations that propose the development of assays for high throughput screening (HTS) relevant to processes and diseases specific to its mission with the intent of using them to screen for small molecule compounds that show desired properties as probes for use in advancing knowledge about the relevant target, identifying new targets, or serving as pre-therapeutic leads. The NIH launched a Molecular Libraries and Imaging initiative as part of the NIH Roadmap for Medical Research to establish a network of HTS screening centers which provide access to a large compound library, robotics to carry out the assays, and informatics to interpret the results (http://mli.nih.gov/mli/). This FOA seeks to establish a stream of scientifically and technologically outstanding assays for screening by these and other academic centers. Assays may involve targets indirectly related to disease, but which might provide insight into the biology of relevant diseases. Other targets might be associated with rare and neglected diseases, an area of increasing focus for the NIH (http://www.nih.gov/news/health/may2009/nhgri-20.htm). Assays should be relevant to the scope of the research for at least one of the sponsoring NIH Institutes. Mechanism of Support. This FOA will utilize the R01 grant mechanism. Funds Available and Anticipated Number of Awards. Because the nature and scope of the proposed research will vary from application to application, it is anticipated that the size and duration of each award will also vary. The total amount awarded and the number of awards will depend upon the mechanism numbers, quality, duration, and costs of the applications received. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/pa-files/PA-10-213.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV Email:FBOWebmaster@OD.NIH.GOV |
Related Documents
There are no related documents on this grant.
Packages
| Agency Contact Information: | NIH OER Webmaster FBOWebmaster@OD.NIH.GOV Email: FBOWebmaster@OD.NIH.GOV |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| ADOBE-FORMS-B1 | Supersedes ADOBE-FORMS-B | PKG00021907 | Oct 15, 2010 | Sep 07, 2013 | View | |
| ADOBE-FORMS-B | Use for submissions intended for due dates of January 25, 2010 and beyond | PKG00019128 | Sep 05, 2010 | Oct 15, 2010 | View |
Package 1
Mandatory forms
55102 RR_SF424_1_2-1.2.pdf
55102 RR_OtherProjectInfo_1_3-1.3.pdf
55102 RR_KeyPersonExpanded_1_2-1.2.pdf
55102 PerformanceSite_1_4-1.4.pdf
55102 PHS398_ResearchPlan_1_3-1.3.pdf
55102 PHS398_CoverPageSupplement_1_4-1.4.pdf
55102 PHS398_Checklist_1_3-1.3.pdf
Optional forms
55102 RR_Budget-1.1.pdf
55102 RR_SubawardBudget-1.2.pdf
55102 PHS_CoverLetter_1_2-1.2.pdf
55102 PHS398_ModularBudget-1.1.pdf
Package 2
Mandatory forms
55102 RR_SF424_1_2-1.2.pdf
55102 PerformanceSite_1_3-1.3.pdf
55102 RR_OtherProjectInfo_1_2-1.2.pdf
55102 RR_KeyPersonExpanded_1_2-1.2.pdf
55102 PHS398_CoverPageSupplement_1_4-1.4.pdf
55102 PHS398_ResearchPlan_1_3-1.3.pdf
55102 PHS398_Checklist_1_3-1.3.pdf
Optional forms
55102 PHS_CoverLetter_1_2-1.2.pdf
55102 PHS398_ModularBudget-1.1.pdf
55102 RR_Budget-1.1.pdf
55102 RR_SubawardBudget-1.2.pdf
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