This National Cancer Institute (NCI) grant is for supporting the advanced development and rigorous validation of emerging technologies aimed at improving the quality and utility of biological samples used in cancer research and clinical care. It seeks innovative tools, devices, instrumentation, and associated methods that address issues like pre-analytical degradation of analytes during biospecimen collection, processing, handling, and storage. The goal is to preserve sample integrity and establish quality assessment criteria. Successful technologies will have overcome major feasibility gaps and require further validation for broader adoption. By reducing pre-analytical variations, these advancements are expected to significantly accelerate and enhance research across various cancer fields, including biology, early detection, diagnosis, treatment, and addressing health disparities.
Opportunity ID: 351176
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-CA-24-011 |
| Funding Opportunity Title: | Advanced Development and Validation of Emerging Biospecimen Science Technologies for Basic and Clinical Cancer Research (R33 Clinical Trial Not Allowed) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Education Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.394 — Cancer Detection and Diagnosis Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Nov 28, 2023 |
| Last Updated Date: | Nov 28, 2023 |
| Original Closing Date for Applications: | Oct 01, 2024 |
| Current Closing Date for Applications: | Oct 01, 2024 |
| Archive Date: | Nov 06, 2024 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | $300,000 |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Public housing authorities/Indian housing authorities For profit organizations other than small businesses Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Private institutions of higher education Others (see text field entitled “Additional Information on Eligibility” for clarification) State governments County governments Special district governments Small businesses Public and State controlled institutions of higher education Independent school districts City or township governments Native American tribal governments (Federally recognized) |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | This Notice of Funding Opportunity (NOFO) solicits grant applications proposing exploratory research projects focused on further development and validation of emerging technologies that improve the quality of the samples used for cancer research or clinical care. This includes new capabilities to address issues related to pre-analytical degradation of targeted analytes during the collection, processing, handling, and/or storage of cancer-relevant biospecimens. This NOFO solicits R33 applications where major feasibility gaps for the technology or methodology have been overcome, as demonstrated with supportive preliminary data, but still requires further development and rigorous validation to encourage adoption by the research community. The overall goal is to support the development of highly innovative technologies capable of maximizing or otherwise interrogating the quality and utility of biological samples used for downstream analyses. This NOFO will support the development of tools, devices, instrumentation, and associated methods to preserve or protect sample integrity, or establish verification criteria for quality assessment/quality control and handling under diverse conditions. These technologies are expected to accelerate and/or enhance research in cancer biology, early detection and screening, clinical diagnosis, treatment, epidemiology, or address issues associated with cancer health disparities, by reducing pre-analytical variations that affect biospecimen sample quality. |
| Link to Additional Information: | https://grants.nih.gov/grants/guide/rfa-files/RFA-CA-24-011.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH Grants Information
grantsinfo@nih.gov Email:grantsinfo@nih.gov |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
Folder 351176 Full Announcement-RFA-CA-24-011 -> RFA-CA-24-011-Full-Announcement.pdf
Packages
| Agency Contact Information: | NIH Grants Information grantsinfo@nih.gov Email: grantsinfo@nih.gov |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-H | Use for due dates on or after January 25, 2023 | PKG00283922 | Mar 01, 2024 | Oct 01, 2024 | View |
Package 1
Mandatory forms
351176 RR_SF424_5_0-5.0.pdf
351176 PHS398_CoverPageSupplement_5_0-5.0.pdf
351176 RR_OtherProjectInfo_1_4-1.4.pdf
351176 PerformanceSite_4_0-4.0.pdf
351176 RR_KeyPersonExpanded_4_0-4.0.pdf
351176 RR_Budget_3_0-3.0.pdf
351176 PHS398_ResearchPlan_5_0-5.0.pdf
351176 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
351176 RR_SubawardBudget30_3_0-3.0.pdf
351176 PHS_AssignmentRequestForm_3_0-3.0.pdf
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