The National Institutes of Health (NIH) is offering this grant to advance the understanding of cardiovascular disease (CVD) in individuals with type 1 diabetes (T1D). This initiative expands the Cardiovascular Repository for T1D (CaRe-T1D), aiming to establish a comprehensive biorepository of human cardiovascular tissue and a robust scientific consortium. CVD progression in T1D uniquely differs from type 2 diabetes, highlighting a significant and often residual health risk. CaRe-T1D actively collects hearts, kidneys, arteries, and blood samples from organ donors, including those with and without diabetes. This grant is for attracting new investigative teams to leverage these extensive resources through collaborative studies, fostering discovery and mechanistic research to elucidate the pathogenesis of CVD specific to T1D, ultimately improving patient outcomes.
Opportunity ID: 351242
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-DK-23-021 |
| Funding Opportunity Title: | Cardiovascular Repository Type 1 Diabetes (CARE-T1D) Consortium (U01 Clinical Trial Not Allowed). |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Cooperative Agreement |
| Category of Funding Activity: | Food and Nutrition Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.233 — National Center on Sleep Disorders Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Nov 30, 2023 |
| Last Updated Date: | Nov 30, 2023 |
| Original Closing Date for Applications: | Apr 11, 2024 |
| Current Closing Date for Applications: | Apr 11, 2024 |
| Archive Date: | May 17, 2024 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | $600,000 |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Public housing authorities/Indian housing authorities County governments Public and State controlled institutions of higher education For profit organizations other than small businesses Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Small businesses Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Private institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments) Native American tribal governments (Federally recognized) Special district governments State governments Independent school districts Others (see text field entitled “Additional Information on Eligibility” for clarification) City or township governments |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | Cardiovascular complications are the leading cause of death for individuals with type 1 diabetes (T1D) and significantly shorten their lives. Cardiovascular disease (CVD) progression in people with T1D differs from that observed in people with type 2 diabetes (T2D) and residual increased risk of CVD remains after treatment of standard risk factors, such as hyperglycemia, hypertension, and hyperlipidemia. The NIH Cardiovascular Repository for T1D (CaRe-T1D) was initiated with the goal of establishing a biorepository of human CV tissue and a scientific consortium to advance and support discovery and mechanistic research that increase the understanding of CVD in T1D. The first phase launched the biorepository and now in the second phase investigative teams will be added to form a consortium with the biorepository serving as the Coordinating Center (CC). CaRe-T1D is currently collecting hearts, kidneys, carotid and peripheral arteries, and blood from organ donors with T1D, T2D and without diabetes. The goal of this NOFO is to attract investigative teams with complementary interests and expertise who will leverage these resources through individual and collaborative studies to advance our knowledge of the pathogenesis of CVD in T1D. |
| Link to Additional Information: | https://grants.nih.gov/grants/guide/rfa-files/RFA-DK-23-021.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH Grants Information
grantsinfo@nih.gov Email:grantsinfo@nih.gov |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
Folder 351242 Full Announcement-RFA-DK-23-021 -> RFA-DK-23-021-Full-Announcement.pdf
Packages
| Agency Contact Information: | NIH Grants Information grantsinfo@nih.gov Email: grantsinfo@nih.gov |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-H | Use for due dates on or after January 25, 2023 | PKG00283969 | Mar 11, 2024 | Apr 11, 2024 | View |
Package 1
Mandatory forms
351242 RR_SF424_5_0-5.0.pdf
351242 PHS398_CoverPageSupplement_5_0-5.0.pdf
351242 RR_OtherProjectInfo_1_4-1.4.pdf
351242 PerformanceSite_4_0-4.0.pdf
351242 RR_KeyPersonExpanded_4_0-4.0.pdf
351242 PHS398_ResearchPlan_5_0-5.0.pdf
351242 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
351242 RR_Budget_3_0-3.0.pdf
351242 RR_SubawardBudget30_3_0-3.0.pdf
351242 PHS398_ModularBudget_1_2-1.2.pdf
351242 PHS_AssignmentRequestForm_3_0-3.0.pdf
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