The National Cancer Institute (NCI) offers a grant to establish Research Centers for Cancer Systems Biology. These multi-project Centers will apply systems biology to address basic cancer biology challenges. Projects must be hypothesis-driven, integrating quantitative experimentation, analysis, modeling, and validation in disease-relevant contexts. Centers are required to form interdisciplinary teams with quantitative and cancer biology expertise. Key priorities include sharing interoperable datasets, developing community-accessible tools, fostering active collaboration within the consortium, and cultivating a diverse research community. This grant supports a coordinated, integrated approach to complex cancer problems.
Opportunity ID: 335044
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-CA-21-048 |
| Funding Opportunity Title: | Research Centers for Cancer Systems Biology (U54 Clinical Trial Not Allowed) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Cooperative Agreement |
| Category of Funding Activity: | Education Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.396 — Cancer Biology Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Jul 30, 2021 |
| Last Updated Date: | Jul 30, 2021 |
| Original Closing Date for Applications: | Oct 19, 2022 |
| Current Closing Date for Applications: | Oct 19, 2022 |
| Archive Date: | Nov 24, 2022 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | $1,500,000 |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | State governments Private institutions of higher education Others (see text field entitled “Additional Information on Eligibility” for clarification) For profit organizations other than small businesses County governments Native American tribal organizations (other than Federally recognized tribal governments) Public and State controlled institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Small businesses Special district governments Public housing authorities/Indian housing authorities Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Independent school districts City or township governments Native American tribal governments (Federally recognized) |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | The National Cancer Institutes (NCI) Cancer Systems Biology Consortium (CSBC, https://csbconsortium.org/) supports the application of systems biology approaches to cancer research and includes U01 Research Projects and, through this FOA, U54 Research Centers. These multi-project Centers should address challenges in basic cancer biology that would benefit from a coordinated systems biology approach and should coalesce around a well-defined overarching scientific theme pursued through two or three research projects. The research projects should be driven by a specific hypothesis and incorporate iterative cycles of quantitative experimentation, analysis, modeling, and validation in a disease-relevant context. Centers will include an interdisciplinary research team including quantitative and cancer biology expertise, administrative management, optional shared resource cores, and an Outreach core that support the overall Center research theme. Each Center will make sharing interoperable datasets and community accessible tools a priority with the support of a multi-consortium U24 Coordinating Center (being solicited under RFA-CA-21-049), actively collaborate within and outside the consortium, and support a welcoming and diverse research community at the Center and Consortium level. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/rfa-files/RFA-CA-21-048.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
grantsinfo@nih.gov Email:grantsinfo@nih.gov |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
Folder 335044 Full Announcement-RFA-CA-21-048 -> RFA-CA-21-048-Full-Announcement.pdf
Packages
| Agency Contact Information: | NIH OER Webmaster grantsinfo@nih.gov Email: grantsinfo@nih.gov |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-F | Use for due dates on or before January 24, 2022 | PKG00268390 | Oct 12, 2021 | Jan 24, 2022 | View | |
| FORMS-G | Use for due dates on or after January 25, 2022 | PKG00269645 | Oct 27, 2021 | Oct 19, 2022 | View |
Package 1
Mandatory forms
335044 RR_SF424_2_0-2.0.pdf
335044 PHS398_CoverPageSupplement_5_0-5.0.pdf
335044 RR_OtherProjectInfo_1_4-1.4.pdf
335044 PerformanceSite_2_0-2.0.pdf
335044 RR_KeyPersonExpanded_2_0-2.0.pdf
335044 PHS398_ResearchPlan_4_0-4.0.pdf
335044 PHSHumanSubjectsAndClinicalTrialsInfo_2_0-2.0.pdf
Optional forms
335044 PHS_Additional_IndirectCosts-1.0.pdf
335044 PHS_AssignmentRequestForm_3_0-3.0.pdf
Package 2
Mandatory forms
335044 RR_SF424_5_0-5.0.pdf
335044 PHS398_CoverPageSupplement_5_0-5.0.pdf
335044 RR_OtherProjectInfo_1_4-1.4.pdf
335044 PerformanceSite_4_0-4.0.pdf
335044 RR_KeyPersonExpanded_4_0-4.0.pdf
335044 PHS398_ResearchPlan_4_0-4.0.pdf
335044 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
335044 PHS_Additional_IndirectCosts_2_0-2.0.pdf
335044 PHS_AssignmentRequestForm_3_0-3.0.pdf
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