This National Institutes of Health (NIH) department is offering this grant to develop sensitive technologies and methods for obtaining high-quality, comprehensive genomic data from human specimens that are easy to collect, handle, and store. This grant is for the purpose of enhancing the availability of nucleic acids-based genomic data for various clinical and research applications. Proposals should cover the entire process from specimen collection and storage to nucleic acid extraction and data acquisition. Developed methods must be comparable to dried blood spot collection in ease, applicable for rapid clinical point-of-care testing, scalable, and cost-effective. The genomic data must match fresh whole blood in quality and comprehensiveness.
Opportunity ID: 231054
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | PAR-13-203 |
| Funding Opportunity Title: | Methods Development for Obtaining Comprehensive Genomic Information from Human Specimens that are Easy to Collect and Store (R43/R44) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Health Income Security and Social Services |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.172 — Human Genome Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Apr 19, 2013 |
| Last Updated Date: | – |
| Original Closing Date for Applications: | Mar 25, 2016 |
| Current Closing Date for Applications: | Mar 25, 2016 |
| Archive Date: | Apr 25, 2016 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Small businesses |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, may be allowed. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | This FOA invites applications to develop sensitive technologies or methods for obtaining high quality and comprehensive nucleic acids-based genomic data from limited quantities of human specimens that are easy to collect, handle, and store. Applications that address all of the steps from the collection of specimens, through storage and nucleic acids extraction, to obtaining genomic data will be considered as having highest priority to this FOA. The ease of proposed sample collection methods should be at least comparable to that of the current dried blood spot collection method. The developed technologies or methods should be applicable to clinical point-of-care testing in terms of speed and ease, and ultimately have the potential to be scalable to high throughput settings, while maintaining cost effectiveness. The genomic data obtained must be at least equivalent to that which can be obtained from fresh whole blood in terms of quality and comprehensiveness. It is expected that the research conducted under this FOA will enhance the availability of comprehensive nucleic acids-based genomic data for various clinical and research applications in need of obtaining genomic data from easy-to-collect and handle human specimens. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/pa-files/PAR-13-203.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV Email:FBOWebmaster@OD.NIH.GOV |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
There are no related documents on this grant.
Packages
| Agency Contact Information: | NIH OER Webmaster FBOWebmaster@OD.NIH.GOV Email: FBOWebmaster@OD.NIH.GOV |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| ADOBE-FORMS-B2 | Adobe-Forms-B2 | PKG00174291 | Jun 28, 2013 | Jan 07, 2015 | View | |
| FORMS-C | Use for due dates on or after August 5, 2014 | PKG00196580 | May 13, 2014 | Mar 25, 2016 | View |
Package 1
Mandatory forms
231054 RR_SF424_1_2-1.2.pdf
231054 PerformanceSite_1_4-1.4.pdf
231054 RR_OtherProjectInfo_1_3-1.3.pdf
231054 RR_KeyPersonExpanded_1_2-1.2.pdf
231054 RR_Budget-1.1.pdf
231054 PHS398_CoverPageSupplement_1_4-1.4.pdf
231054 PHS398_ResearchPlan_1_3-1.3.pdf
231054 PHS398_Checklist_1_3-1.3.pdf
231054 SBIR_STTR_Information_1_1-1.1.pdf
Optional forms
231054 RR_SubawardBudget30-1.2.pdf
231054 PHS_CoverLetter_1_2-1.2.pdf
Package 2
Mandatory forms
231054 RR_SF424_2_0-2.0.pdf
231054 PHS398_ResearchPlan_2_0-2.0.pdf
231054 SBIR_STTR_Information_1_1-1.1.pdf
231054 RR_KeyPersonExpanded_2_0-2.0.pdf
231054 RR_OtherProjectInfo_1_3-1.3.pdf
231054 RR_Budget_1_3-1.3.pdf
231054 PerformanceSite_2_0-2.0.pdf
231054 PHS398_CoverPageSupplement_2_0-2.0.pdf
Optional forms
231054 RR_SubawardBudget30_1_3-1.3.pdf
231054 PlannedReport-1.0.pdf
231054 PHS398_CumulativeInclusionReport-1.0.pdf