This grant from the National Institutes of Health aims to foster studies that deepen the mechanistic understanding of how small vessel vascular changes contribute to cognitive impairment and dementia (VCID). It seeks proposals for developing new technologies and innovative methods. These advancements should enable precise imaging and functional assessment of the brain’s delicate small blood and lymphatic vessels, along with their surrounding perivascular spaces. The ultimate goal is to illuminate the long-term impact of dysfunction in these microvessels on Alzheimer’s disease and related dementias, paving the way for improved diagnostic and therapeutic strategies.
Opportunity ID: 335351
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | PAR-22-026 |
| Funding Opportunity Title: | Selectively Target Technology Development to Understand How Changes or Dysfunction at the Capillary, Arterioles, and Small Lymphatic Vessels Level Can Have Long-term Impact on AD/ADRD (R01 Clinical Trial Not Allowed) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.853 — Extramural Research Programs in the Neurosciences and Neurological Disorders |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Aug 19, 2021 |
| Last Updated Date: | Aug 19, 2021 |
| Original Closing Date for Applications: | Nov 08, 2021 |
| Current Closing Date for Applications: | Nov 08, 2021 |
| Archive Date: | Dec 14, 2021 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | $499,000 |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education State governments Others (see text field entitled “Additional Information on Eligibility” for clarification) Public and State controlled institutions of higher education Special district governments Independent school districts Small businesses County governments For profit organizations other than small businesses Private institutions of higher education Native American tribal governments (Federally recognized) Native American tribal organizations (other than Federally recognized tribal governments) City or township governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Public housing authorities/Indian housing authorities |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | The purpose of this Funding Opportunity Announcement (FOA) is to solicit studies that will advance the mechanistic understanding of small vessel vascular contributions to cognitive impairment and dementia (VCID) through the development of new technologies and innovative methods that enable the imaging and/or functional assessment of the small blood and lymphatic vessels and perivascular spaces of the brain. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/pa-files/PAR-22-026.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
OERWebmaster03@od.nih.gov Email:OERWebmaster03@od.nih.gov |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
There are no related documents on this grant.
Packages
| Agency Contact Information: | NIH OER Webmaster OERWebmaster03@od.nih.gov Email: OERWebmaster03@od.nih.gov |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-G | Use for due dates on or after January 25, 2022 | PKG00269846 | Oct 28, 2021 | Nov 08, 2021 | View | |
| FORMS-F | Use for due dates on or before January 24, 2022 | PKG00268627 | Oct 08, 2021 | Jan 24, 2022 | View |
Package 1
Mandatory forms
335351 RR_SF424_5_0-5.0.pdf
335351 PHS398_CoverPageSupplement_5_0-5.0.pdf
335351 RR_OtherProjectInfo_1_4-1.4.pdf
335351 PerformanceSite_4_0-4.0.pdf
335351 RR_KeyPersonExpanded_4_0-4.0.pdf
335351 PHS398_ResearchPlan_4_0-4.0.pdf
335351 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
335351 RR_Budget_3_0-3.0.pdf
335351 RR_SubawardBudget30_3_0-3.0.pdf
335351 PHS398_ModularBudget_1_2-1.2.pdf
335351 PHS_AssignmentRequestForm_3_0-3.0.pdf
Package 2
Mandatory forms
335351 RR_SF424_2_0-2.0.pdf
335351 PHS398_CoverPageSupplement_5_0-5.0.pdf
335351 RR_OtherProjectInfo_1_4-1.4.pdf
335351 PerformanceSite_2_0-2.0.pdf
335351 RR_KeyPersonExpanded_2_0-2.0.pdf
335351 PHS398_ResearchPlan_4_0-4.0.pdf
335351 PHSHumanSubjectsAndClinicalTrialsInfo_2_0-2.0.pdf
Optional forms
335351 RR_Budget_1_4-1.4.pdf
335351 RR_SubawardBudget30_1_4-1.4.pdf
335351 PHS398_ModularBudget_1_2-1.2.pdf
335351 PHS_AssignmentRequestForm_3_0-3.0.pdf
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