This grant by the Department of Health focuses on researching the clinical, epidemiologic, and ecologic factors impacting the burden and distribution of Monkeypox in the Tshuapa District of the Democratic Republic of the Congo. The project aims to study the ecology, epidemiology, treatment, and prevention of Monkeypox, along with other vaccine-preventable diseases in the region. Researchers will investigate ecologic risk factors, transmission modes, develop diagnostic assays, and evaluate interventions to improve medical outcomes and reduce the spread of Monkeypox in at-risk communities. Applications are open until January 13, 2014.
Opportunity ID: 247576
General Information
| Document Type:: | Grants Notice |
| Funding Opportunity Number:: | RFA-CK-14-002 |
| Funding Opportunity Title:: | Clinical, Epidemiologic and Ecologic Factors Impacting the Burden and Distribution of Monkeypox in Tshuapa District, Democratic Republic of the Congo |
| Opportunity Category:: | Discretionary |
| Opportunity Category Explanation:: | |
| Funding Instrument Type:: | |
| Category of Funding Activity:: | Health |
| Category Explanation:: | |
| Expected Number of Awards:: | 1 |
| Assistance Listings Number(s):: | 93.084 — Prevention of Disease, Disability, and Death by Infectious Diseases |
| Cost Sharing or Matching Requirement:: | No |
| Version:: | Synopsis 2 |
| Posted Date:: | Nov 13, 2013 |
| Last Updated Date:: | Nov 21, 2013 |
| Original Closing Date for Applications:: | Jan 13, 2014 |
| Current Closing Date for Applications:: | Jan 13, 2014 |
| Archive Date:: | Feb 12, 2014 |
| Estimated Total Program Funding:: | $ 1,500,000 |
| Award Ceiling:: | $500,000 |
| Award Floor:: | $0 |
Eligibility
| Eligible Applicants:: | Others (see text field entitled “Additional Information on Eligibility” for clarification) |
| Additional Information on Eligibility:: | Eligible Applicants: Kinshasa School of Public Health (KSPH), University of Kinshasa, Mont Amba, Kinshasa, Democratic Republic of the Congo |
Additional Information
| Agency Name:: | Centers for Disease Control and Prevention – ERA |
| Description:: | This project encompasses a three-year program of research activities to be accomplished beginning FY14 and continuing through FY17, with annual renewal contingent on satisfactory performance during the previous 12 months. The research opportunity entails investigating (1) the ecology and epidemiology of monkeypox (MPX) as well as (2) the treatment and prevention of monkeypox illnesses in humans. This research opportunity may also extend to other vaccine-preventable diseases that are of importance to the Democratic Republic of the Congo (DRC). Human monkeypox (MPX) is a smallpox-like illness which is endemic in parts of the Congo Basin and occurs sporadically elsewhere in western sub-Saharan Africa. Currently, nearly all of the cases that are reported annually to WHO occur in the DRC. Monkeypox has epidemic potential and is recognized as a significant threat to human health in the DRC. This research opportunity will allow investigators to develop a better understanding of the ecology and epidemiology of MPX and potentially other vaccine-preventable diseases and will lead to the development of improved strategies for MPX surveillance, diagnosis, prevention, and treatment. The specific goals set out for this research opportunity are as follows:1. Identification of ecologic factors that place humans at risk of infection including identification of sylvatic host(s) of MPX virus;2. Determination of the principle modes of inter-human and zoonotic transmission of MPX virus;3. Development and evaluation of novel methodologies for enhanced MPX surveillance and rapid or point-of-care diagnostic assays;4. Identification and evaluation of interventions to improve medical outcomes and reduce the introduction and spread of MPX in at-risk communities. |
| Link to Additional Information:: | |
| Grantor Contact Information:: | If you have difficulty accessing the full announcement electronically, please contact: |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
| Synopsis 2 | Updated Application Instructions. | Nov 21, 2013 |
| Synopsis 1 |
Package Status
Below are CLOSED Opportunity Package(s) no longer available for this Funding Opportunity:
Package No: 1
| Assistance Listings: | 93.084 |
| Competition ID: | NCEZID-R |
| Competition Title: | NCEZID-R |
| Opportunity Package ID: | PKG00189433 |
| Opening Date: | Nov 13, 2013 |
| Closing Date: | Jan 13, 2014 |
| Agency Contact Information:: | CDC |
| Who Can Apply:: | Organization Applicants |
| mendatory_forms |
SF424 (R & R) [V1.2] Project/Performance Site Location(s) [V1.4] Research And Related Other Project Information [V1.3] Research And Related Senior/Key Person Profile (Expanded) [V1.2] Research & Related Budget [V1.1] PHS 398 Cover Page Supplement [V1.4] PHS 398 Research Plan [V1.3] PHS 398 Checklist [V1.3] |
| optional_forms |
R & R Subaward Budget Attachment(s) Form 5 YR 30 ATT [V1.2] PHS Cover Letter [V1.2] |
Packages
| Assistance Listings | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions | Who Can Apply: | |
|---|---|---|---|---|---|---|---|---|
| 93.084 | NCEZID-R | NCEZID-R | PKG00189433 | Nov 13, 2013 | Jan 13, 2014 | View | CDC | Organization Applicants |