This National Institutes of Health (NIH) grant is for the final five-year phase of the Knockout Mouse Phenotyping Project (KOMP2). Its primary purpose is to establish a comprehensive resource of null-mutant mice and associated phenotype data to elucidate functional information for every mammalian protein-coding gene. Specifically, the project aims to generate approximately 1,200 mutant mouse lines using CRISPR/Cas9 technology, perform extensive phenotyping assays, cryopreserve germplasm, and ensure these valuable mice and data are readily accessible to the broader research community. This Funding Opportunity Announcement represents a limited competition, exclusively inviting applications from recipient organizations previously funded under RFA-RM-15-017.
Opportunity ID: 335502
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-HG-21-036 |
| Funding Opportunity Title: | Limited Competition: Knockout Mouse Production and Phenotyping Project (UM1) Clinical Trial Not Allowed |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Cooperative Agreement |
| Category of Funding Activity: | Education Environment Food and Nutrition Health Income Security and Social Services |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.113 — Environmental Health |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Sep 01, 2021 |
| Last Updated Date: | Sep 01, 2021 |
| Original Closing Date for Applications: | Nov 01, 2021 |
| Current Closing Date for Applications: | Nov 01, 2021 |
| Archive Date: | Dec 07, 2021 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | City or township governments Independent school districts Small businesses Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Public housing authorities/Indian housing authorities Native American tribal governments (Federally recognized) Special district governments State governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments) Private institutions of higher education Others (see text field entitled “Additional Information on Eligibility” for clarification) For profit organizations other than small businesses Public and State controlled institutions of higher education County governments |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | The purpose of the Knockout Mouse Phenotyping Project (KOMP2) is to produce a comprehensive resource of null-mutant mice, and associated phenotype data, for the purpose of elucidating functional information for each protein-coding gene in the mammalian genome. This Funding Opportunity Announcement (FOA) solicits applications for production and phenotyping centers that will make maximum progress toward completion of KOMP2 in a final five-year project period. The specific objectives are to generate approximately 1,200 mutant mouse lines using CRISPR/Cas9 technology, perform a series of phenotyping assays, cryopreserve germplasm, and make mice and data readily available to the research community. This is a limited competition RFA. Only recipient organizations funded under (RFA-RM-15-017) are eligible to apply. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/rfa-files/RFA-HG-21-036.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
OERWebmaster03@od.nih.gov Email:OERWebmaster03@od.nih.gov |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
There are no related documents on this grant.
Packages
| Agency Contact Information: | NIH OER Webmaster OERWebmaster03@od.nih.gov Email: OERWebmaster03@od.nih.gov |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-F | Use for due dates on or before January 24, 2022 | PKG00268760 | Oct 01, 2021 | Jan 24, 2022 | View |
Package 1
Mandatory forms
335502 RR_SF424_2_0-2.0.pdf
335502 PHS398_CoverPageSupplement_5_0-5.0.pdf
335502 RR_OtherProjectInfo_1_4-1.4.pdf
335502 PerformanceSite_2_0-2.0.pdf
335502 RR_KeyPersonExpanded_2_0-2.0.pdf
335502 RR_Budget_1_4-1.4.pdf
335502 PHS398_ResearchPlan_4_0-4.0.pdf
335502 PHSHumanSubjectsAndClinicalTrialsInfo_2_0-2.0.pdf
Optional forms
335502 RR_SubawardBudget30_1_4-1.4.pdf
335502 PHS_AssignmentRequestForm_3_0-3.0.pdf
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