This grant from the Human BioMolecular Atlas Program (HuBMAP) supports the establishment of state-of-the-art Tissue Mapping Centers (TMCs). These centers will be core data generators for the HuBMAP Consortium, focused on creating high-resolution, multi-parameter, 3D atlases of non-diseased human organs. Successful TMCs will develop and standardize robust pipelines for generating, validating, and analyzing data from advanced imaging and omics technologies. This involves optimizing the entire process from tissue collection to data integration and interpretation to construct comprehensive maps. The resulting atlases will offer novel insights into cellular organization affecting tissue function, individual variations, and lifespan changes. By grant conclusion, centers must have produced integrated, multi-scale molecular, cellular, and morphological maps from multiple donors for a published organ reference atlas.
Opportunity ID: 335710
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-RM-21-026 |
| Funding Opportunity Title: | Tissue Mapping Centers for the Human BioMolecular Atlas Program (U54 Clinical Trial Not Allowed) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Cooperative Agreement |
| Category of Funding Activity: | Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.310 — Trans-NIH Research Support |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Sep 14, 2021 |
| Last Updated Date: | Sep 14, 2021 |
| Original Closing Date for Applications: | Nov 19, 2021 |
| Current Closing Date for Applications: | Nov 19, 2021 |
| Archive Date: | Dec 25, 2021 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | State governments County governments Private institutions of higher education Native American tribal governments (Federally recognized) Public housing authorities/Indian housing authorities For profit organizations other than small businesses City or township governments Native American tribal organizations (other than Federally recognized tribal governments) Special district governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Public and State controlled institutions of higher education Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Independent school districts Small businesses Others (see text field entitled “Additional Information on Eligibility” for clarification) |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | This FOA seeks to support state-of-the-art Tissue Mapping Centers (TMCs) that will serve as the core data generators for the HuBMAP Consortium by generating a high-resolution, multi-parameter, 3D atlas of a non-diseased human organ. Successful centers will build, benchmark, and standardize pipelines for generating, validating and analyzing data from multiplexed, high-throughput imaging and omics technologies. Centers will be expected to integrate and optimize all parts of the data generation pipeline, from tissue collection and preservation through to data integration, analysis and interpretation in order to build high-resolution maps. Centers will use these maps to provide new insights into intra-, inter- and extra- cellular organizational features that influence tissue function, vary across individuals or that change across the lifespan. By the end of four years of funding, a successful center will have created a significant number of high-resolution, multi-scale, multi-dimensional molecular, cellular and morphological maps from multiple donors that are integrated into a published reference atlas for that organ. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/rfa-files/RFA-RM-21-026.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
OERWebmaster03@od.nih.gov Email:OERWebmaster03@od.nih.gov |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
There are no related documents on this grant.
Packages
| Agency Contact Information: | NIH OER Webmaster OERWebmaster03@od.nih.gov Email: OERWebmaster03@od.nih.gov |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-G | Use for due dates on or after January 25, 2022 | PKG00269649 | Oct 27, 2021 | Nov 19, 2021 | View | |
| FORMS-F | Use for due dates on or before January 24, 2022 | PKG00268950 | Oct 19, 2021 | Jan 24, 2022 | View |
Package 1
Mandatory forms
335710 RR_SF424_5_0-5.0.pdf
335710 PHS398_CoverPageSupplement_5_0-5.0.pdf
335710 RR_OtherProjectInfo_1_4-1.4.pdf
335710 PerformanceSite_4_0-4.0.pdf
335710 RR_KeyPersonExpanded_4_0-4.0.pdf
335710 PHS398_ResearchPlan_4_0-4.0.pdf
335710 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
335710 PHS_Additional_IndirectCosts_2_0-2.0.pdf
335710 PHS_AssignmentRequestForm_3_0-3.0.pdf
Package 2
Mandatory forms
335710 RR_SF424_2_0-2.0.pdf
335710 PHS398_CoverPageSupplement_5_0-5.0.pdf
335710 RR_OtherProjectInfo_1_4-1.4.pdf
335710 PerformanceSite_2_0-2.0.pdf
335710 RR_KeyPersonExpanded_2_0-2.0.pdf
335710 PHS398_ResearchPlan_4_0-4.0.pdf
335710 PHSHumanSubjectsAndClinicalTrialsInfo_2_0-2.0.pdf
Optional forms
335710 PHS_Additional_IndirectCosts-1.0.pdf
335710 PHS_AssignmentRequestForm_3_0-3.0.pdf
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