The Department of Defense (DoD) is offering the Breast Cancer Breakthrough Award, a new grant mechanism supporting promising research with potential for major breakthroughs in breast cancer. This grant aims to accelerate progress toward ending breast cancer by funding projects that yield significant, transformative impact beyond incremental advancements. Researchers can propose projects ranging from small to large-scale, at various development stages. Four distinct funding levels are available, accommodating innovative, high-risk/high-reward early-stage research (Level 1, no preliminary data) through studies with preliminary data (Level 2), advanced translational projects with near-term clinical potential (Level 3), up to large-scale initiatives designed to revolutionize clinical management with expected near-term clinical impact (Level 4).
Opportunity ID: 234217
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | W81XWH-13-BCRP-BREAKTHROUGH |
| Funding Opportunity Title: | DoD Breast Cancer Breakthrough Award |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Cooperative Agreement Grant |
| Category of Funding Activity: | Science and Technology and other Research and Development |
| Category Explanation: | – |
| Expected Number of Awards: | 50 |
| Assistance Listings: | 12.420 — Military Medical Research and Development |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | May 10, 2013 |
| Last Updated Date: | – |
| Original Closing Date for Applications: | Sep 25, 2013 |
| Current Closing Date for Applications: | Sep 25, 2013 |
| Archive Date: | Oct 25, 2013 |
| Estimated Total Program Funding: | $75,000,000 |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled “Additional Information on Eligibility” |
| Additional Information on Eligibility: | – |
Additional Information
| Agency Name: | Dept. of the Army — USAMRAA |
| Description: | The BCRP Breakthrough Award mechanism is being offered for the first time in FY13. The intent of the Breakthrough Award is to support promising research that has the potential to lead to or make breakthroughs in breast cancer. The critical components of this award mechanism are: Impact: Research supported by the Breakthrough Award will have the potential for a major impact and accelerate progress toward ending breast cancer. The impact may be near-term or long-term, but must be significant and move beyond an incremental advancement. Applications must articulate the pathway to making an impact for breast cancer patients, even if clinical impact is not an immediate outcome. Research Scope: Research proposed under this award mechanism may be small- to large-scale projects, at different stages of idea and research development. Four different funding levels, based on the scope of the research, are available for this award mechanism. It is the responsibility of the Principal Investigator (PI) to select the funding level that is most appropriate for the research proposed. The following are general descriptions, although not all-inclusive, of the scope of research projects that would be appropriate to propose under each funding level: Funding Level 1: Innovative, high-risk/high-reward research that is in the earliest stages of idea development. Research with potential to yield new avenues of investigation. Proof of concept. No preliminary data available. Funding Level 2: Research that is already supported by preliminary data and has potential to make significant advancements toward translation from the laboratory to the clinic. Demonstration of efficacy in in vivo models, as applicable. Funding Level 3: Advanced translational studies that have potential for near-term clinical investigation. Small-scale clinical trials may apply. Funding Level 4: Large-scale projects that will transform and revolutionize the clinical management of breast cancer. Near-term clinical impact is expected. PIs are expected to have experience in successfully leading large-scale projects. Note: An invited oral presentation to the BCRP Integration Panel (IP) is a requirement for application review of Level 4 |
| Link to Additional Information: | – |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
CDMRP Help Desk
301-682-5507 help@cdmrp.org Email:help@cdmrp.org |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
Folder 234217 Full Announcement-1 -> breakthrough award preapplication form_gg.pdf
Folder 234217 Full Announcement-1 -> fy13 bcrp breakthrough pa_gg.pdf
Packages
| Agency Contact Information: | CDMRP Help Desk 301-682-5507 help@cdmrp.org Email: help@cdmrp.org |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| 12.420 | PKG00177453 | May 10, 2013 | Sep 25, 2013 | View |
Package 1
Mandatory forms
234217 RR_SF424_1_2-1.2.pdf
234217 PerformanceSite_1_4-1.4.pdf
234217 RR_Budget-1.1.pdf
Optional forms
234217 RR_SubawardBudget30-1.2.pdf
234217 RR_KeyPersonExpanded_1_2-1.2.pdf
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