This grant is for developing and enhancing advanced technologies that improve the functionality, quality, scope, and throughput of perturbation-induced cellular signature data generation. Its purpose is to accelerate data acquisition and broaden the range of identifiable signatures for large-scale efforts like The Library of Integrated Network-Based Cellular Signatures (LINCS). This U01 mechanism complements existing LINCS initiatives focused on data production and computational tool development. Up to four awards are anticipated, with budgets reaching $500,000 in direct costs annually for a maximum of two years, supporting innovative proposals to advance cellular signature science.
Opportunity ID: 56452
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-RM-10-004 |
| Funding Opportunity Title: | Advanced Technologies for Detection of Perturbation-Induced Cellular Signatures (U01) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Cooperative Agreement |
| Category of Funding Activity: | Health |
| Category Explanation: | – |
| Expected Number of Awards: | 4 |
| Assistance Listings: | 93.310 — Trans-NIH Research Support |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Aug 06, 2010 |
| Last Updated Date: | – |
| Original Closing Date for Applications: | Feb 22, 2011 |
| Current Closing Date for Applications: | Feb 22, 2011 |
| Archive Date: | Mar 25, 2011 |
| Estimated Total Program Funding: | $5,600,000 |
| Award Ceiling: | $500,000 |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Others (see text field entitled “Additional Information on Eligibility” for clarification) Public housing authorities/Indian housing authorities For profit organizations other than small businesses Small businesses Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Native American tribal governments (Federally recognized) Native American tribal organizations (other than Federally recognized tribal governments) Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Private institutions of higher education Independent school districts Special district governments County governments City or township governments Public and State controlled institutions of higher education State governments |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Eligible Agencies of the Federal Government; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | Purpose. This FOA encourages grant applications that propose to develop or substantially adapt technologies and methodologies designed to significantly improve the functionality, quality, scope, and/or throughput of perturbation-induced cellular signature data generation. The technologies generated through this FOA are anticipated to accelerate the rate of data generation and the range of signatures that can be identified and characterized by large scale high-throughput perturbation-induced signature collection efforts like The Library of Integrated Network-Based Cellular Signatures (LINCS). Mechanism of Support. This FOA will utilize the U01 award mechanism. It is intended to complement RFA-RM-10-003, Large Scale Production of Perturbagen-Induced Cellular Signatures (U54),that establishes data production efforts to systematize approaches for identifying mechanism-based associations among the effects of disparate biological perturbations and a knowledge base to study functional relationships among the responding cellular components. Released in parallel with this FOA is RFA-RM-10-005, Computational Tool Development and Integrative Data Analysis for LINCS (U01), which seeks to develop innovative computational tools and approaches for the integrative analysis of multiple types of data generated within LINCS. Funds Available and Anticipated Number of Awards. We expect to fund up to four awards in FY2011. Total funds available for the initiative are $2.8M in each of FY2011 and FY2012, contingent upon receiving scientifically meritorious proposals. For this funding opportunity, budgets up to $500,000 direct costs per year and time periods up to two years may be requested. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/rfa-files/RFA-RM-10-004.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV Email:FBOWebmaster@OD.NIH.GOV |
Version History
| Version | Modification Description | Updated Date |
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