The National Institutes of Health is offering this grant to establish multi-scale computational models that replicate dynamic changes linked to aging and Alzheimer’s Disease (AD) and AD-Related Dementias (ADRD). This grant is for researchers aiming to utilize diverse computational approaches, including mathematical and computational modeling, image analysis, artificial intelligence, and machine learning. The primary purpose is to deepen our understanding of aging processes and AD/ADRD, examining them across various levels of biological organization—from molecules and cells to networks, and ultimately, to cognition and behavior. This initiative seeks innovative computational solutions to unravel complex neurological dynamics.
Opportunity ID: 352211
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-AG-25-016 |
| Funding Opportunity Title: | Multi-Scale Models Bridging Levels of Analysis in Aging and Alzheimer’s Disease (AD) and AD-Related Dementias (ADRD) (R01 Clinical Trial Not Allowed) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.866 — Aging Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Feb 06, 2024 |
| Last Updated Date: | Feb 06, 2024 |
| Original Closing Date for Applications: | Jun 13, 2024 |
| Current Closing Date for Applications: | Jun 13, 2024 |
| Archive Date: | Jul 19, 2024 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | $500,000 |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Public and State controlled institutions of higher education Native American tribal governments (Federally recognized) Independent school districts Others (see text field entitled “Additional Information on Eligibility” for clarification) Native American tribal organizations (other than Federally recognized tribal governments) County governments For profit organizations other than small businesses Small businesses Private institutions of higher education Special district governments Public housing authorities/Indian housing authorities Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education City or township governments State governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | The purpose of this funding opportunity is to invite applications proposing to establish multi-scale computational models recapitulating dynamic changes associated with aging and Alzheimers disease and Alzheimers disease-related dementias (AD/ADRD). This broad scope encompasses a variety of computational approachessuch as mathematical and computational modeling, image analysis, artificial intelligence, and machine learningto better understand aging processes and AD/ADRD across molecules, cells and networks, and cognition and behavior. |
| Link to Additional Information: | https://grants.nih.gov/grants/guide/rfa-files/RFA-AG-25-016.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH Grants Information
grantsinfo@nih.gov Email:grantsinfo@nih.gov |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
Folder 352211 Full Announcement-RFA-AG-25-016 -> RFA-AG-25-016-Full-Announcement.pdf
Packages
| Agency Contact Information: | NIH Grants Information grantsinfo@nih.gov Email: grantsinfo@nih.gov |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-H | Use for due dates on or after January 25, 2023 | PKG00284732 | May 13, 2024 | Jun 13, 2024 | View |
Package 1
Mandatory forms
352211 RR_SF424_5_0-5.0.pdf
352211 PHS398_CoverPageSupplement_5_0-5.0.pdf
352211 RR_OtherProjectInfo_1_4-1.4.pdf
352211 PerformanceSite_4_0-4.0.pdf
352211 RR_KeyPersonExpanded_4_0-4.0.pdf
352211 PHS398_ResearchPlan_5_0-5.0.pdf
352211 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
352211 RR_Budget_3_0-3.0.pdf
352211 RR_SubawardBudget30_3_0-3.0.pdf
352211 PHS398_ModularBudget_1_2-1.2.pdf
352211 PHS_AssignmentRequestForm_3_0-3.0.pdf
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