The National Cancer Institute (NCI) is offering this grant to establish multiple multi-institutional, transdisciplinary Translational Research Centers, forming the core of the Barretts Esophagus Translational Research Network (BETRNet). This grant is for the purpose of advancing our understanding of esophageal adenocarcinoma (EA) biology, improving cancer risk stratification and prediction, developing effective prevention strategies, and better identifying individuals at risk for EA. These BETRNet Centers will conduct innovative, high-impact research to develop validated diagnostic tools and enhance patient management. Collaborative efforts among the centers, facilitated by a separate Coordinating Center, are expected to accelerate the integration of research findings into clinical applications. The NCI has allocated $6.0 million for FY2011, with $30 million over five years, expecting to fund three to four awards under this Cooperative Agreement (U54) mechanism.
Opportunity ID: 56611
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-CA-10-014 |
| Funding Opportunity Title: | Barretts Esophagus Translational Research Network (U54) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Cooperative Agreement |
| Category of Funding Activity: | Education Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.393 — Cancer Cause and Prevention Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Aug 13, 2010 |
| Last Updated Date: | – |
| Original Closing Date for Applications: | Jan 05, 2011 |
| Current Closing Date for Applications: | Jan 05, 2011 |
| Archive Date: | Feb 05, 2011 |
| Estimated Total Program Funding: | $1,500,000 |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | County governments Public and State controlled institutions of higher education For profit organizations other than small businesses Others (see text field entitled “Additional Information on Eligibility” for clarification) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Private institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education State governments City or township governments |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Regional Organizations; U.S. Territory or Possession. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | Purpose. This National Cancer Institute funding opportunity announcement (FOA) solicits applications for multi-institutional, transdisciplinary, Translational Research Centers to serve as the main components of the Barretts Esophagus Translational Research Network (BETRNet). The BETRNet overall objective is to achieve a better understanding of esophageal adenocarcinoma (EA) biology, improve EA cancer risk stratification and prediction, provide strategies for EA prevention, and better define individuals at risk. In addition to three to four Translational Research Centers (to be supported under this FOA), BETRNet will include a single Coordinating Center (to be supported under a parallel FOA). Translational Research Centers are designed to conduct innovative, high impact transdiciplinary research that will ultimately lead to development of validated diagnostic tools as well as improved patient management. The BETRNet is also expected to foster productive collaborations among individual Research Centers. The activities of the Research Centers will be facilitated by the Coordinating Center in four major areas: Network coordination; data management and bioinformatics; patient registry with virtual biorepository; and Network evaluation. Through these collaborative efforts, BETRNet can accelerate the integration and transformation of important research findings generated from individual laboratory-based, clinical, or population studies into clinical applications. Mechanism of Support. This FOA will utilize the NIH Cooperative Agreement Specialized Centers (U54) funding mechanism. This FOA is parallel to a separate FOA (RFA-CA-10-015) utilizing the U01 funding mechanism to support the Coordinating Center. Funds Available and Anticipated Number of Awards. For this FOA, the NCI has committed $6.0M in total costs for FY2011 and $30M in total costs over a 5-year period. Three or four awards are expected in connection with this FOA. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/rfa-files/RFA-CA-10-014.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV Email:FBOWebmaster@OD.NIH.GOV |
Version History
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