The National Institutes of Health (NIH) is offering this grant to support research focused on identifying cell-specific mechanisms in biomolecular condensate (BMC) formation and function. This initiative specifically targets the role of BMCs in diverse cell types within the context of aging and the neurobiology of Alzheimer’s disease (AD) or AD-related dementias (ADRD). This grant is for enhancing our understanding of the cell-specific mechanistic role BMCs play in these conditions. The research aims to lay the groundwork for more comprehensive etiological studies, which could ultimately lead to the development of novel BMC-based therapies for age-related neurodegenerative diseases.
Opportunity ID: 336333
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-AG-23-002 |
| Funding Opportunity Title: | Cell-Specific Impact of Liquid-Liquid Phase Separation in Aging and AD/ADRD (R21 Clinical Trial Not Allowed) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.866 — Aging Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Oct 28, 2021 |
| Last Updated Date: | Oct 28, 2021 |
| Original Closing Date for Applications: | Mar 03, 2022 |
| Current Closing Date for Applications: | Mar 03, 2022 |
| Archive Date: | Apr 08, 2022 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | $275,000 |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Native American tribal organizations (other than Federally recognized tribal governments) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Small businesses Independent school districts Native American tribal governments (Federally recognized) State governments City or township governments Private institutions of higher education County governments Special district governments Public and State controlled institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education For profit organizations other than small businesses Others (see text field entitled “Additional Information on Eligibility” for clarification) Public housing authorities/Indian housing authorities |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | The goal of this Funding Opportunity Announcement (FOA) is to support research to identify cell-specific mechanisms in biomolecular condensate (BMC) formation and function, providing novel information for the role BMCs play in diverse cell types in the context of aging and neurobiology of Alzheimers disease (AD) or AD-related dementias (ADRD). This research should enhance our understanding of the cell-specific mechanistic role of BMCs in aging and AD/ADRD and serve as the foundation for more comprehensive etiological studies that might lead to the development of future BMC-based therapies for age-related neurodegenerative diseases. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/rfa-files/RFA-AG-23-002.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
OERWebmaster03@od.nih.gov Email:OERWebmaster03@od.nih.gov |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
Folder 336333 Full Announcement-RFA-AG-23-002 -> RFA-AG-23-002-Full-Announcement.pdf
Packages
| Agency Contact Information: | NIH OER Webmaster OERWebmaster03@od.nih.gov Email: OERWebmaster03@od.nih.gov |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-G | Use for due dates on or after January 25, 2022 | PKG00270333 | Feb 03, 2022 | Mar 03, 2022 | View |
Package 1
Mandatory forms
336333 RR_SF424_5_0-5.0.pdf
336333 PHS398_CoverPageSupplement_5_0-5.0.pdf
336333 RR_OtherProjectInfo_1_4-1.4.pdf
336333 PerformanceSite_4_0-4.0.pdf
336333 RR_KeyPersonExpanded_4_0-4.0.pdf
336333 PHS398_ResearchPlan_4_0-4.0.pdf
336333 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
336333 RR_Budget_3_0-3.0.pdf
336333 RR_SubawardBudget30_3_0-3.0.pdf
336333 PHS398_ModularBudget_1_2-1.2.pdf
336333 PHS_AssignmentRequestForm_3_0-3.0.pdf
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