The National Eye Institute (NEI) is offering this grant through its Audacious Goal Initiative (AGI), which seeks to push the boundaries of vision science. This initiative aims to restore sight by regenerating specific retinal cells, including photoreceptors and retinal ganglion cells, critical for processing and transmitting visual information to the brain. While research has demonstrated success in regenerating retinal neurons and connections in animal models like fish and mice, the AGI’s ultimate objective is to achieve vision restoration in humans. This grant specifically supports the planning phases for future regenerative medicine clinical trials, laying the groundwork for innovative human treatments rather than funding the trials themselves.
Opportunity ID: 336543
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | PAR-22-070 |
| Funding Opportunity Title: | NEI Regenerative Medicine Clinical Trial Planning Grant (R34 – Clinical Trials Not Allowed) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.867 — Vision Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 2 |
| Posted Date: | Nov 16, 2021 |
| Last Updated Date: | Jan 19, 2022 |
| Original Closing Date for Applications: | Jan 07, 2025 |
| Current Closing Date for Applications: | Jan 19, 2022 |
| Archive Date: | Feb 12, 2025 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | $150,000 |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Small businesses Private institutions of higher education City or township governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education For profit organizations other than small businesses Public housing authorities/Indian housing authorities Special district governments Native American tribal governments (Federally recognized) Independent school districts Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education State governments County governments Native American tribal organizations (other than Federally recognized tribal governments) Others (see text field entitled “Additional Information on Eligibility” for clarification) Public and State controlled institutions of higher education |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: |
The National Eye Institute (NEI) Audacious Goal Initiative (AGI) is an effort to push the boundaries of vision science and restore vision through regeneration of cells in the retina. AGI research specifically targets photoreceptors (PRCs) and retinal ganglion cells (RGCs) in the eye. Photoreceptors often called rods and cones are cells in the retina that, when stimulated by light, generate signals the brain perceives as images. The retinal ganglion cells carry these signals from the photoreceptors to the brain. Although there has been some success in regenerating retinal neurons and connections in fish, mice, and other systems, the ultimate goal of the AGI is to restore vision in humans. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/pa-files/PAR-22-070.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
OERWebmaster03@od.nih.gov Email:OERWebmaster03@od.nih.gov |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
| Terminating FOA due to issuance of NOT-EY-22-003 | Jan 19, 2022 | |
| Nov 16, 2021 |
DISPLAYING: Synopsis 2
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | PAR-22-070 |
| Funding Opportunity Title: | NEI Regenerative Medicine Clinical Trial Planning Grant (R34 – Clinical Trials Not Allowed) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.867 — Vision Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 2 |
| Posted Date: | Nov 16, 2021 |
| Last Updated Date: | Jan 19, 2022 |
| Original Closing Date for Applications: | Jan 07, 2025 |
| Current Closing Date for Applications: | Jan 19, 2022 |
| Archive Date: | Feb 12, 2025 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | $150,000 |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Small businesses Private institutions of higher education City or township governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education For profit organizations other than small businesses Public housing authorities/Indian housing authorities Special district governments Native American tribal governments (Federally recognized) Independent school districts Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education State governments County governments Native American tribal organizations (other than Federally recognized tribal governments) Others (see text field entitled “Additional Information on Eligibility” for clarification) Public and State controlled institutions of higher education |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: |
The National Eye Institute (NEI) Audacious Goal Initiative (AGI) is an effort to push the boundaries of vision science and restore vision through regeneration of cells in the retina. AGI research specifically targets photoreceptors (PRCs) and retinal ganglion cells (RGCs) in the eye. Photoreceptors often called rods and cones are cells in the retina that, when stimulated by light, generate signals the brain perceives as images. The retinal ganglion cells carry these signals from the photoreceptors to the brain. Although there has been some success in regenerating retinal neurons and connections in fish, mice, and other systems, the ultimate goal of the AGI is to restore vision in humans. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/pa-files/PAR-22-070.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
OERWebmaster03@od.nih.gov Email:OERWebmaster03@od.nih.gov |
DISPLAYING: Synopsis 1
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | PAR-22-070 |
| Funding Opportunity Title: | NEI Regenerative Medicine Clinical Trial Planning Grant (R34 – Clinical Trials Not Allowed) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.867 — Vision Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Nov 16, 2021 |
| Last Updated Date: | Nov 16, 2021 |
| Original Closing Date for Applications: | – |
| Current Closing Date for Applications: | Jan 07, 2025 |
| Archive Date: | Feb 12, 2025 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | $150,000 |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | State governments County governments Others (see text field entitled “Additional Information on Eligibility” for clarification) Private institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education For profit organizations other than small businesses Public housing authorities/Indian housing authorities Independent school districts Native American tribal governments (Federally recognized) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education City or township governments Special district governments Native American tribal organizations (other than Federally recognized tribal governments) Small businesses Public and State controlled institutions of higher education |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | The National Eye Institute (NEI) Audacious Goal Initiative (AGI) is an effort to push the boundaries of vision science and restore vision through regeneration of cells in the retina. AGI research specifically targets photoreceptors (PRCs) and retinal ganglion cells (RGCs) in the eye. Photoreceptors often called rods and cones are cells in the retina that, when stimulated by light, generate signals the brain perceives as images. The retinal ganglion cells carry these signals from the photoreceptors to the brain. Although there has been some success in regenerating retinal neurons and connections in fish, mice, and other systems, the ultimate goal of the AGI is to restore vision in humans. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/pa-files/PAR-22-070.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
OERWebmaster03@od.nih.gov Email:OERWebmaster03@od.nih.gov |
Related Documents
Folder 336543 Full Announcement-PAR-22-070 -> PAR-22-070-Full-Announcement.pdf
Packages
| Agency Contact Information: | NIH OER Webmaster OERWebmaster03@od.nih.gov Email: OERWebmaster03@od.nih.gov |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-F | Use for due dates on or before January 24, 2022 | PKG00270345 | Jan 16, 2022 | Jan 20, 2022 | View | |
| FORMS-H | Use for due dates on or before January 24, 2025 | PKG00278275 | Nov 10, 2022 | Jan 24, 2025 | View |
Package 1
Mandatory forms
336543 RR_SF424_2_0-2.0.pdf
336543 PHS398_CoverPageSupplement_5_0-5.0.pdf
336543 RR_OtherProjectInfo_1_4-1.4.pdf
336543 PerformanceSite_2_0-2.0.pdf
336543 RR_KeyPersonExpanded_2_0-2.0.pdf
336543 PHS398_ResearchPlan_4_0-4.0.pdf
336543 PHSHumanSubjectsAndClinicalTrialsInfo_2_0-2.0.pdf
Optional forms
336543 RR_Budget_1_4-1.4.pdf
336543 RR_SubawardBudget30_1_4-1.4.pdf
336543 PHS398_ModularBudget_1_2-1.2.pdf
336543 PHS_AssignmentRequestForm_3_0-3.0.pdf
Package 2
Mandatory forms
336543 RR_SF424_5_0-5.0.pdf
336543 PHS398_CoverPageSupplement_5_0-5.0.pdf
336543 RR_OtherProjectInfo_1_4-1.4.pdf
336543 PerformanceSite_4_0-4.0.pdf
336543 RR_KeyPersonExpanded_4_0-4.0.pdf
336543 PHS398_ResearchPlan_5_0-5.0.pdf
336543 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
336543 RR_Budget_3_0-3.0.pdf
336543 RR_SubawardBudget30_3_0-3.0.pdf
336543 PHS398_ModularBudget_1_2-1.2.pdf
336543 PHS_AssignmentRequestForm_3_0-3.0.pdf
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