The National Institutes of Health (NIH) is offering this U01 grant to expand the public availability of high-quality data on protein-drug ligand complexes. This crucial data supports the development, validation, and benchmarking of drug docking and screening software. This grant is for the primary purpose of fostering more accurate and robust in silico drug screening methods. Such advancements are expected to significantly accelerate drug discovery and reduce development costs by focusing efforts on promising candidate compounds. An additional benefit includes improving the prediction of side effects from off-target binding and increasing the repurposing of existing pharmaceuticals, leading to more efficient drug development.
Opportunity ID: 236600
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-GM-14-010 |
| Funding Opportunity Title: | Drug Docking and Screening Data Resource (U01) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Cooperative Agreement |
| Category of Funding Activity: | Health |
| Category Explanation: | – |
| Expected Number of Awards: | 1 |
| Assistance Listings: | 93.859 — Biomedical Research and Research Training |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 2 |
| Posted Date: | Jun 19, 2013 |
| Last Updated Date: | Oct 18, 2013 |
| Original Closing Date for Applications: | Oct 09, 2013 |
| Current Closing Date for Applications: | Nov 01, 2013 |
| Archive Date: | Dec 01, 2013 |
| Estimated Total Program Funding: | $750,000 |
| Award Ceiling: | $500,000 |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Private institutions of higher education Independent school districts State governments Special district governments For profit organizations other than small businesses Public and State controlled institutions of higher education Public housing authorities/Indian housing authorities City or township governments Small businesses Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education County governments Others (see text field entitled “Additional Information on Eligibility” for clarification) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Native American tribal governments (Federally recognized) Native American tribal organizations (other than Federally recognized tribal governments) |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | The purpose of this Funding Opportunity Announcement (FOA) is to continue to increase the amount of publicly available, high-quality data describing structures and affinities of protein-drug ligand complexes -data vital for development, validation, and benchmarking of drug docking and screening software. Accurate and robust methods for in silico drug screening are expected to speed drug discovery and reduce drug development cost by focusing experimental efforts on the most promising candidate compounds. The ability to predict side effects resulting from off-target binding and to increase repurposing of existing pharmaceuticals is an additional expected benefit. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/rfa-files/RFA-GM-14-010.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV Email:FBOWebmaster@OD.NIH.GOV |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
| Modified Archive Date based on new Expiration Date, per NOT-OD-14-003. | Oct 18, 2013 | |
| Oct 18, 2013 |
DISPLAYING: Synopsis 2
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-GM-14-010 |
| Funding Opportunity Title: | Drug Docking and Screening Data Resource (U01) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Cooperative Agreement |
| Category of Funding Activity: | Health |
| Category Explanation: | – |
| Expected Number of Awards: | 1 |
| Assistance Listings: | 93.859 — Biomedical Research and Research Training |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 2 |
| Posted Date: | Jun 19, 2013 |
| Last Updated Date: | Oct 18, 2013 |
| Original Closing Date for Applications: | Oct 09, 2013 |
| Current Closing Date for Applications: | Nov 01, 2013 |
| Archive Date: | Dec 01, 2013 |
| Estimated Total Program Funding: | $750,000 |
| Award Ceiling: | $500,000 |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Private institutions of higher education Independent school districts State governments Special district governments For profit organizations other than small businesses Public and State controlled institutions of higher education Public housing authorities/Indian housing authorities City or township governments Small businesses Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education County governments Others (see text field entitled “Additional Information on Eligibility” for clarification) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Native American tribal governments (Federally recognized) Native American tribal organizations (other than Federally recognized tribal governments) |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | The purpose of this Funding Opportunity Announcement (FOA) is to continue to increase the amount of publicly available, high-quality data describing structures and affinities of protein-drug ligand complexes -data vital for development, validation, and benchmarking of drug docking and screening software. Accurate and robust methods for in silico drug screening are expected to speed drug discovery and reduce drug development cost by focusing experimental efforts on the most promising candidate compounds. The ability to predict side effects resulting from off-target binding and to increase repurposing of existing pharmaceuticals is an additional expected benefit. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/rfa-files/RFA-GM-14-010.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV Email:FBOWebmaster@OD.NIH.GOV |
DISPLAYING: Synopsis 1
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-GM-14-010 |
| Funding Opportunity Title: | Drug Docking and Screening Data Resource (U01) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Cooperative Agreement |
| Category of Funding Activity: | Health |
| Category Explanation: | – |
| Expected Number of Awards: | 1 |
| Assistance Listings: | 93.859 — Biomedical Research and Research Training |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Oct 18, 2013 |
| Last Updated Date: | – |
| Original Closing Date for Applications: | – |
| Current Closing Date for Applications: | Oct 09, 2013 |
| Archive Date: | Nov 09, 2013 |
| Estimated Total Program Funding: | $750,000 |
| Award Ceiling: | $500,000 |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education For profit organizations other than small businesses Small businesses Public and State controlled institutions of higher education County governments Native American tribal organizations (other than Federally recognized tribal governments) Special district governments Private institutions of higher education State governments Public housing authorities/Indian housing authorities Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Others (see text field entitled “Additional Information on Eligibility” for clarification) Independent school districts City or township governments Native American tribal governments (Federally recognized) |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | The purpose of this Funding Opportunity Announcement (FOA) is to continue to increase the amount of publicly available, high-quality data describing structures and affinities of protein-drug ligand complexes -data vital for development, validation, and benchmarking of drug docking and screening software. Accurate and robust methods for in silico drug screening are expected to speed drug discovery and reduce drug development cost by focusing experimental efforts on the most promising candidate compounds. The ability to predict side effects resulting from off-target binding and to increase repurposing of existing pharmaceuticals is an additional expected benefit. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/rfa-files/RFA-GM-14-010.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV Email:FBOWebmaster@OD.NIH.GOV |
Related Documents
There are no related documents on this grant.
Packages
| Agency Contact Information: | NIH OER Webmaster FBOWebmaster@OD.NIH.GOV Email: FBOWebmaster@OD.NIH.GOV |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| 93.859 | FORMS-C | Use for due dates after 9/24/2013 | PKG00179811 | Sep 09, 2013 | Nov 01, 2013 | View |
Package 1
Mandatory forms
236600 RR_SF424_2_0-2.0.pdf
236600 PHS398_ResearchPlan_2_0-2.0.pdf
236600 PHS398_CoverPageSupplement_2_0-2.0.pdf
236600 RR_KeyPersonExpanded_2_0-2.0.pdf
236600 RR_OtherProjectInfo_1_3-1.3.pdf
236600 PerformanceSite_2_0-2.0.pdf
Optional forms
236600 RR_SubawardBudget30_1_3-1.3.pdf
236600 PlannedReport-1.0.pdf
236600 PHS398_CumulativeInclusionReport-1.0.pdf
236600 PHS398_ModularBudget_1_2-1.2.pdf
236600 RR_Budget_1_3-1.3.pdf
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