This grant from the Health Research Department seeks applications for a randomized clinical trial. The objective is to develop and test a multifactorial strategy aimed at preventing serious fall-related injuries among non-institutionalized older persons. The proposed evidence-based protocol must detail how to screen, assess, and implement targeted interventions for high-risk individuals, ensuring coordination, including medication adjustments. It should also outline monitoring progress and adapting interventions as needed. The strategy must demonstrate feasibility for real-world implementation post-trial. Applicants are encouraged to incorporate patient and stakeholder perspectives, and consider adaptive study designs to enhance learning from accumulating evidence, ultimately aiming for a highly effective and implementable solution to reduce fall-related harm.
Opportunity ID: 237725
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-AG-14-009 |
| Funding Opportunity Title: | Clinical Trial of a Multifactorial Fall Injury Prevention Strategy in Older Persons (U01) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Cooperative Agreement |
| Category of Funding Activity: | Health |
| Category Explanation: | – |
| Expected Number of Awards: | 1 |
| Assistance Listings: | 93.866 — Aging Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Jul 16, 2013 |
| Last Updated Date: | – |
| Original Closing Date for Applications: | Nov 13, 2013 |
| Current Closing Date for Applications: | Nov 13, 2013 |
| Archive Date: | Dec 14, 2013 |
| Estimated Total Program Funding: | $30,000,000 |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Special district governments County governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education For profit organizations other than small businesses State governments City or township governments Public and State controlled institutions of higher education Small businesses Independent school districts Native American tribal governments (Federally recognized) Private institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments) Public housing authorities/Indian housing authorities Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Others (see text field entitled “Additional Information on Eligibility” for clarification) |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are not allowed. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | This initiative invites applications for funding to conduct a randomized clinical trial of a multifactorial strategy for preventing serious fall-related injuries among non-institutionalized older persons. A multifactorial strategy should be designed for maximal potency in reducing the rate of serious fall-related injuries, which (if found to be effective in the trial) is feasible for future implementation with fidelity in practice in at least one type of care setting. The trial should test an evidence-based protocol that articulates decision rules that address: screening the population to identify individuals at high risk for falling, assessing high-risk individuals to define their specific risk factors, selecting interventions to ameliorate each persons risk factors, implementing these interventions, coordinating the delivery of each persons set of interventions (including methods for coordinating decisions on possible adjustments in medication prescribing among multiple prescribers for a given patient), monitoring each persons progress toward risk factor reduction, and implementing alternative interventions to overcome lack of progress and mitigate new risk factors. The study should incorporate patients and other relevant stakeholders priorities and perspectives in the specification of the study protocol and the outcomes to be measured. Applicants should consider adaptive study design features that facilitate “learning” from accumulating positive or negative evidence. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/rfa-files/RFA-AG-14-009.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV Email:FBOWebmaster@OD.NIH.GOV |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
There are no related documents on this grant.
Packages
| Agency Contact Information: | NIH OER Webmaster FBOWebmaster@OD.NIH.GOV Email: FBOWebmaster@OD.NIH.GOV |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| 93.866 | FORMS-C | Forms-C | PKG00181034 | Oct 13, 2013 | Nov 13, 2013 | View |
Package 1
Mandatory forms
237725 RR_SF424_2_0-2.0.pdf
237725 PHS398_ResearchPlan_2_0-2.0.pdf
237725 PHS398_CoverPageSupplement_2_0-2.0.pdf
237725 RR_KeyPersonExpanded_2_0-2.0.pdf
237725 RR_OtherProjectInfo_1_3-1.3.pdf
237725 PerformanceSite_2_0-2.0.pdf
Optional forms
237725 RR_SubawardBudget30_1_3-1.3.pdf
237725 PlannedReport-1.0.pdf
237725 PHS398_CumulativeInclusionReport-1.0.pdf
237725 PHS398_ModularBudget_1_2-1.2.pdf
237725 RR_Budget_1_3-1.3.pdf
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