This NIMH grant is for evaluating the preliminary effectiveness of therapeutic and service delivery interventions that utilize lethal means safety strategies to reduce suicide risk in healthcare and community settings. Despite promising results in some clinical settings, there is a need for strong evidence on these strategies in broader healthcare and community contexts. This pilot research aims to advance knowledge on optimization strategies, therapeutic change mechanisms, and provide preliminary data on how lethal means safety interventions improve safety and lower suicide risk. The trials should assess feasibility, tolerability, acceptability, safety, and potential effectiveness, engaging underlying mechanisms. This data will serve as a prerequisite for larger, definitive effectiveness trials.
Opportunity ID: 353021
General Information
Document Type: | Grants Notice |
Funding Opportunity Number: | RFA-MH-25-120 |
Funding Opportunity Title: | Lethal Means Safety Suicide Prevention Research in Healthcare and Community Settings (R34 Clinical Trial Required) |
Opportunity Category: | Discretionary |
Opportunity Category Explanation: | – |
Funding Instrument Type: | Grant |
Category of Funding Activity: | Health |
Category Explanation: | – |
Expected Number of Awards: | – |
Assistance Listings: | 93.242 — Mental Health Research Grants |
Cost Sharing or Matching Requirement: | No |
Version: | Synopsis 1 |
Posted Date: | Mar 18, 2024 |
Last Updated Date: | Mar 18, 2024 |
Original Closing Date for Applications: | Jan 23, 2025 |
Current Closing Date for Applications: | Jan 23, 2025 |
Archive Date: | Feb 28, 2025 |
Estimated Total Program Funding: | – |
Award Ceiling: | – |
Award Floor: | – |
Eligibility
Eligible Applicants: | Private institutions of higher education Independent school districts Others (see text field entitled “Additional Information on Eligibility” for clarification) Public and State controlled institutions of higher education County governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Native American tribal governments (Federally recognized) Small businesses Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education City or township governments State governments Native American tribal organizations (other than Federally recognized tribal governments) For profit organizations other than small businesses Special district governments Public housing authorities/Indian housing authorities |
Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are not allowed. |
Additional Information
Agency Name: | National Institutes of Health |
Description: | NIMH seeks applications to evaluate the preliminary effectiveness of therapeutic and service delivery interventions that utilize lethal means safety strategies to reduce suicide risk in healthcare and community settings. Behavioral health clinics that incorporate lethal means counseling into their programming have been associated with significant reductions in suicide attempts and death. Yet, the field is lacking strong evidence on the effectiveness of these strategies tested in healthcare and community settings. Pilot effectiveness research will advance knowledge regarding optimization strategies, therapeutic change mechanisms, and inform decisions about whether further effectiveness testing is warranted. The research will provide preliminary evidence on the extent to which lethal means safety interventions more optimally lead to improved safety (e.g., number/percent of firearms safely stored, overdose injury codes for an individual) and lower suicide risk. In this pilot phase of effectiveness research, the trial should be designed to evaluate the feasibility, tolerability, acceptability, safety, and potential effectiveness of the approach; to address whether the intervention engages the target(s)/mechanisms(s) that is/are presumed to underlie the intervention effects; and to obtain preliminary data needed as a pre-requisite to a larger-scale effectiveness trial (e.g., comparative effectiveness study, practical trial) designed to definitively test the effectiveness of the intervention. |
Link to Additional Information: | https://grants.nih.gov/grants/guide/rfa-files/RFA-MH-25-120.html |
Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH Grants Information
grantsinfo@nih.gov Email:grantsinfo@nih.gov |
Version History
Version | Modification Description | Updated Date |
---|---|---|
Related Documents
Folder 353021 Full Announcement-RFA-MH-25-120 -> RFA-MH-25-120-Full-Announcement.pdf
Packages
Agency Contact Information: | NIH Grants Information grantsinfo@nih.gov Email: grantsinfo@nih.gov |
Who Can Apply: | Organization Applicants |
Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
---|---|---|---|---|---|---|
FORMS-H | Use for due dates on or before January 24, 2025 | PKG00285405 | Jun 15, 2024 | Jan 24, 2025 | View |
Package 1
Mandatory forms
353021 RR_SF424_5_0-5.0.pdf
353021 PHS398_CoverPageSupplement_5_0-5.0.pdf
353021 RR_OtherProjectInfo_1_4-1.4.pdf
353021 PerformanceSite_4_0-4.0.pdf
353021 RR_KeyPersonExpanded_4_0-4.0.pdf
353021 PHS398_ResearchPlan_5_0-5.0.pdf
353021 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
353021 RR_Budget_3_0-3.0.pdf
353021 RR_SubawardBudget30_3_0-3.0.pdf
353021 PHS398_ModularBudget_1_2-1.2.pdf
353021 PHS_AssignmentRequestForm_3_0-3.0.pdf