This grant supports research to advance the epidemiology of HIV transmission and treatment among high-risk populations in Latin America. Investigators will establish large, electronically-generated cohorts of HIV-negative men who have sex with men, transgender women, people who inject drugs, and/or female sex workers. Participants will be followed to study HIV incidence and viral suppression among those who seroconvert. The research aims to identify areas of high HIV incidence, uncover personal and structural vulnerabilities to infection, and inform on optimal HIV treatment strategies within Latin American countries. Additionally, the grant encourages piloting evidence-based digital (mHealth/online) interventions to reduce HIV incidence and improve treatment outcomes for vulnerable populations.
Opportunity ID: 353259
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-AI-24-009 |
| Funding Opportunity Title: | Limited Interaction Targeted Epidemiology: Epidemiology of Transmission and Treatment of HIV Among People Who Are at Increased Risk for HIV Infection in Latin America (LITE-LA) (UG3/UH3 Clinical Trial Optional) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Cooperative Agreement |
| Category of Funding Activity: | Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.855 — Allergy and Infectious Diseases Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Mar 28, 2024 |
| Last Updated Date: | Mar 28, 2024 |
| Original Closing Date for Applications: | Jul 30, 2024 |
| Current Closing Date for Applications: | Jul 30, 2024 |
| Archive Date: | Sep 04, 2024 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Public housing authorities/Indian housing authorities State governments City or township governments Special district governments County governments Native American tribal organizations (other than Federally recognized tribal governments) Independent school districts For profit organizations other than small businesses Private institutions of higher education Others (see text field entitled “Additional Information on Eligibility” for clarification) Native American tribal governments (Federally recognized) Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Small businesses Public and State controlled institutions of higher education Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | The purpose of this notice of funding opportunity (NOFO) is to support investigators who will form large, electronically-generated cohorts in Latin America of HIV-negative men who have sex with men (MSM), transgender women (TGW), people who inject drugs (PWID), and/or female sex-workers and follow them to study the epidemiology of HIV incidence. Continued follow-up of those persons who acquire HIV will be required to study the epidemiology of viral suppression. Comparisons of participants by seroconverstion status will provide information on geographic and socially defined areas of high HIV incidence as well as on both personal and structural vulnerabilities to HIV infection. Among participants who seroconvert, comparisons of those becoming rapidly engaged in care and who reach non-detectable HIV levels to those whose virus remains detectable will inform on the treatment of HIV in Latin American countries. This NOFO will allow digital trials to determine optimal study approaches, or to pilot evidence-based digital (mHealth and online) HIV prevention and treatment interventions to both reduce HIV incidence and improve treatment in the most vulnerable populations. |
| Link to Additional Information: | https://grants.nih.gov/grants/guide/rfa-files/RFA-AI-24-009.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH Grants Information
grantsinfo@nih.gov Email:grantsinfo@nih.gov |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
Folder 353259 Full Announcement-RFA-AI-24-009 -> RFA-AI-24-009-Full-Announcement.pdf
Packages
| Agency Contact Information: | NIH Grants Information grantsinfo@nih.gov Email: grantsinfo@nih.gov |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-H | Use for due dates on or after January 25, 2023 | PKG00285626 | Jun 30, 2024 | Jul 30, 2024 | View |
Package 1
Mandatory forms
353259 RR_SF424_5_0-5.0.pdf
353259 PHS398_CoverPageSupplement_5_0-5.0.pdf
353259 RR_OtherProjectInfo_1_4-1.4.pdf
353259 PerformanceSite_4_0-4.0.pdf
353259 RR_KeyPersonExpanded_4_0-4.0.pdf
353259 RR_Budget10_3_0-3.0.pdf
353259 PHS398_ResearchPlan_5_0-5.0.pdf
353259 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
353259 RR_SubawardBudget10_30_3_0-3.0.pdf
353259 PHS_AssignmentRequestForm_3_0-3.0.pdf
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