This grant is for resolving critical immunologic and physiologic barriers that hinder safe and efficacious xenotransplantation. The program seeks applications to participate in the multi-center Immunobiology of Xenotransplantation Cooperative Research Program (IXCRP), dedicated to advancing research in this field. Projects will focus on preclinical pig to nonhuman primate or human decedent models for key organs, including pancreatic islet, kidney, heart, lung, or liver xenotransplantation. The funding aims to facilitate collaborative research that addresses the complex biological challenges of cross-species organ transplantation, ultimately paving the way for future clinical applications by overcoming rejection and physiological incompatibilities. This initiative supports a comprehensive approach to enhance the long-term success of xenotransplantation.
Opportunity ID: 353309
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-AI-24-019 |
| Funding Opportunity Title: | Immunobiology of Xenotransplantation (U01 Clinical Trial Not Allowed) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Cooperative Agreement |
| Category of Funding Activity: | Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.855 — Allergy and Infectious Diseases Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Apr 01, 2024 |
| Last Updated Date: | Apr 01, 2024 |
| Original Closing Date for Applications: | Aug 09, 2024 |
| Current Closing Date for Applications: | Aug 09, 2024 |
| Archive Date: | Sep 14, 2024 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Independent school districts City or township governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Private institutions of higher education Native American tribal governments (Federally recognized) Public and State controlled institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments) For profit organizations other than small businesses Small businesses Special district governments County governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education State governments Others (see text field entitled “Additional Information on Eligibility” for clarification) Public housing authorities/Indian housing authorities |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | The purpose of this notice of funding opportunity (NOFO) is to solicit applications to participate in the Immunobiology of Xenotransplantation Cooperative Research Program (IXCRP), a multi-center program dedicated to resolving immunologic and physiologic barriers to safe and efficacious xenotransplantation using preclinical pig to nonhuman primate (NHP) or human decedent models of pancreatic islet, kidney, heart, lung, or liver xenotransplantation. |
| Link to Additional Information: | https://grants.nih.gov/grants/guide/rfa-files/RFA-AI-24-019.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH Grants Information
grantsinfo@nih.gov Email:grantsinfo@nih.gov |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
Folder 353309 Full Announcement-RFA-AI-24-019 -> RFA-AI-24-019-Full-Announcement.pdf
Packages
| Agency Contact Information: | NIH Grants Information grantsinfo@nih.gov Email: grantsinfo@nih.gov |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-H | Use for due dates on or after January 25, 2023 | PKG00285664 | Jul 09, 2024 | Aug 09, 2024 | View |
Package 1
Mandatory forms
353309 RR_SF424_5_0-5.0.pdf
353309 PHS398_CoverPageSupplement_5_0-5.0.pdf
353309 RR_OtherProjectInfo_1_4-1.4.pdf
353309 PerformanceSite_4_0-4.0.pdf
353309 RR_KeyPersonExpanded_4_0-4.0.pdf
353309 PHS398_ResearchPlan_5_0-5.0.pdf
353309 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
353309 RR_Budget_3_0-3.0.pdf
353309 RR_SubawardBudget30_3_0-3.0.pdf
353309 PHS398_ModularBudget_1_2-1.2.pdf
353309 PHS_AssignmentRequestForm_3_0-3.0.pdf
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