This grant, offered by the National Institutes of Health, is for adapting and validating adult biomarkers for use in pediatric care. The purpose is to enhance pediatric diagnosis, prognosis, and the assessment of disease progression, toxicity, and therapeutic response by applying well-established adult biomarkers to children. Eligible projects must focus on biomarkers extensively studied in adults with strong evidence for pediatric application, correlating with clinical observations. This funding opportunity specifically excludes the discovery of new biomarkers for drug development or preclinical studies. It also does not support research on biomarkers for diseases unique to children that lack adult correlates. The aim is to leverage existing knowledge from adult medicine to improve pediatric outcomes.
Opportunity ID: 239017
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | PAR-13-296 |
| Funding Opportunity Title: | Biomarkers: Bridging Pediatric and Adult Therapeutics (R01) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Health Income Security and Social Services |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.865 — Child Health and Human Development Extramural Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Aug 01, 2013 |
| Last Updated Date: | – |
| Original Closing Date for Applications: | Sep 07, 2016 |
| Current Closing Date for Applications: | Sep 07, 2016 |
| Archive Date: | Oct 08, 2016 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Others (see text field entitled “Additional Information on Eligibility” for clarification) State governments Private institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments) Public housing authorities/Indian housing authorities Special district governments Public and State controlled institutions of higher education Native American tribal governments (Federally recognized) Independent school districts County governments Small businesses Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education For profit organizations other than small businesses City or township governments |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | This Funding Opportunity Announcement (FOA) encourages grant applications that propose adapting adult biomarkers to children. This would include the application and validation of biomarkers developed in adults to pediatric diagnosis, prognosis, and estimation of disease progression, toxicity and response to therapy.
Projects supported by this FOA will be confined to those biomarkers that correlate with a clinical observation, have been extensively studied in adults, and for which there is solid evidence that they have pediatric applications. Discovery of new biomarkers for use in new drug development or in preclinical studies is not part of this FOA. Also excluded are biomarkers for diseases that are unique to children and have no adult correlates. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/pa-files/PAR-13-296.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV Email:FBOWebmaster@OD.NIH.GOV |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
There are no related documents on this grant.
Packages
| Agency Contact Information: | NIH OER Webmaster FBOWebmaster@OD.NIH.GOV Email: FBOWebmaster@OD.NIH.GOV |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| 93.865 | FORMS-C | Forms-C | PKG00182295 | Sep 05, 2013 | May 07, 2016 | View |
| FORMS-D | Use for due dates on or after May 25, 2016 | PKG00222109 | Apr 17, 2016 | Sep 07, 2016 | View |
Package 1
Mandatory forms
239017 RR_SF424_2_0-2.0.pdf
239017 PHS398_ResearchPlan_2_0-2.0.pdf
239017 PHS398_CoverPageSupplement_2_0-2.0.pdf
239017 RR_KeyPersonExpanded_2_0-2.0.pdf
239017 RR_OtherProjectInfo_1_3-1.3.pdf
239017 PerformanceSite_2_0-2.0.pdf
Optional forms
239017 RR_SubawardBudget30_1_3-1.3.pdf
239017 PlannedReport-1.0.pdf
239017 PHS398_CumulativeInclusionReport-1.0.pdf
239017 PHS398_ModularBudget_1_2-1.2.pdf
239017 RR_Budget_1_3-1.3.pdf
Package 2
Mandatory forms
239017 RR_SF424_2_0-2.0.pdf
239017 PHS398_CoverPageSupplement_3_0-3.0.pdf
239017 RR_OtherProjectInfo_1_3-1.3.pdf
239017 PerformanceSite_2_0-2.0.pdf
239017 RR_KeyPersonExpanded_2_0-2.0.pdf
239017 PHS398_ResearchPlan_3_0-3.0.pdf
Optional forms
239017 RR_Budget_1_3-1.3.pdf
239017 RR_SubawardBudget30_1_3-1.3.pdf
239017 PHS398_ModularBudget_1_2-1.2.pdf
239017 PHS_Inclusion_Enrollment_Report-1.0.pdf
239017 PHS_AssignmentRequestForm-1.0.pdf
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