This NIH grant is seeking applications to advance research on the continuum between substance use disorders (SUD) and mental health disorders (MHD). The National Institutes of Health is offering this grant to characterize how neuromodulation affects brain circuits and behaviors common to both SUD and MHD. The purpose of this grant is to encourage studies that specify inclusion criteria to capture symptom variance, measure circuit-level target engagement, and assess dimensional cognition and behavior. This research aims to utilize circuit dynamics to understand neurobehavioral function, ultimately developing descriptive models of the shared and distinct dysfunctions across these critical health conditions.
Opportunity ID: 353531
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-DA-25-035 |
| Funding Opportunity Title: | Using Neuromodulation to Characterize the Continuum of Pathophysiology Between Substance Use and Mental Health Disorders (R01 Clinical Trial Required) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Education Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.279 — Drug Abuse and Addiction Research Programs |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Apr 15, 2024 |
| Last Updated Date: | Apr 15, 2024 |
| Original Closing Date for Applications: | Aug 15, 2024 |
| Current Closing Date for Applications: | Aug 15, 2024 |
| Archive Date: | Sep 20, 2024 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Independent school districts County governments Small businesses Others (see text field entitled “Additional Information on Eligibility” for clarification) City or township governments Native American tribal organizations (other than Federally recognized tribal governments) For profit organizations other than small businesses Native American tribal governments (Federally recognized) State governments Public housing authorities/Indian housing authorities Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Public and State controlled institutions of higher education Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Special district governments Private institutions of higher education |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | This NOFO seeks applications from the SUD and MHD research communities that coordinate efforts to characterize the effects of neuromodulation on brain circuits and behaviors relevant to both SUD and MHD. To accomplish this goal, studies would specify inclusion/exclusion criteria to capture variance in both SUD and MHD symptoms. Further, studies would include measures of engagement of circuit-level targets in response to neuromodulation and dimensional measures of cognition and behavior relevant to both SUD and MHD. This research approach uses circuit dynamics to understand neurobehavioral function and to develop ecologically valid and descriptive models of the shared and discrete dysfunction across these conditions. |
| Link to Additional Information: | https://grants.nih.gov/grants/guide/rfa-files/RFA-DA-25-035.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH Grants Information
grantsinfo@nih.gov Email:grantsinfo@nih.gov |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
Folder 353531 Full Announcement-RFA-DA-25-035 -> RFA-DA-25-035-Full-Announcement.pdf
Packages
| Agency Contact Information: | NIH Grants Information grantsinfo@nih.gov Email: grantsinfo@nih.gov |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-H | Use for due dates on or after January 25, 2023 | PKG00285859 | Jul 15, 2024 | Aug 15, 2024 | View |
Package 1
Mandatory forms
353531 RR_SF424_5_0-5.0.pdf
353531 PHS398_CoverPageSupplement_5_0-5.0.pdf
353531 RR_OtherProjectInfo_1_4-1.4.pdf
353531 PerformanceSite_4_0-4.0.pdf
353531 RR_KeyPersonExpanded_4_0-4.0.pdf
353531 PHS398_ResearchPlan_5_0-5.0.pdf
353531 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
353531 RR_Budget_3_0-3.0.pdf
353531 RR_SubawardBudget30_3_0-3.0.pdf
353531 PHS398_ModularBudget_1_2-1.2.pdf
353531 PHS_AssignmentRequestForm_3_0-3.0.pdf
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