The NIH HEAL Initiative is offering this U19 grant to support research aimed at unraveling the complex biological underpinnings of human pain. This funding opportunity is for multidisciplinary teams to leverage human tissue and cell samples, applying large-scale, high-throughput methods to generate comprehensive datasets. The primary purpose of this grant is to discover and characterize functional genetic elements, epigenetic signatures, and molecular/cellular pathways involved in human pain transduction, transmission, and processing. Operating within the NIH HEAL Initiative’s PRECISION Human Pain program, U19 Centers will form a cooperative network, collaborating closely and coordinating data curation and integration with a designated Data Coordination and Integration Center, ultimately advancing our understanding of pain.
Opportunity ID: 337841
General Information
Document Type: | Grants Notice |
Funding Opportunity Number: | RFA-NS-22-018 |
Funding Opportunity Title: | HEAL Initiative: Discovery and Functional Evaluation of Human Pain-associated Genes and Cells (U19 Clinical Trial Not Allowed) |
Opportunity Category: | Discretionary |
Opportunity Category Explanation: | – |
Funding Instrument Type: | Cooperative Agreement |
Category of Funding Activity: | Education Food and Nutrition Health Income Security and Social Services |
Category Explanation: | – |
Expected Number of Awards: | – |
Assistance Listings: | 93.121 — Oral Diseases and Disorders Research |
Cost Sharing or Matching Requirement: | No |
Version: | Synopsis 1 |
Posted Date: | Feb 04, 2022 |
Last Updated Date: | Feb 04, 2022 |
Original Closing Date for Applications: | Mar 09, 2023 |
Current Closing Date for Applications: | Mar 09, 2023 |
Archive Date: | Apr 14, 2023 |
Estimated Total Program Funding: | – |
Award Ceiling: | $1,500,000 |
Award Floor: | – |
Eligibility
Eligible Applicants: | Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Private institutions of higher education Independent school districts City or township governments Small businesses Public and State controlled institutions of higher education Native American tribal governments (Federally recognized) Special district governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Public housing authorities/Indian housing authorities Native American tribal organizations (other than Federally recognized tribal governments) County governments For profit organizations other than small businesses State governments Others (see text field entitled “Additional Information on Eligibility” for clarification) |
Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession. |
Additional Information
Agency Name: | National Institutes of Health |
Description: | The purpose of this funding opportunity announcement is to support research that uses human tissue or cells to generate comprehensive datasets for the discovery and characterization of functional genetic elements, epigenetic signatures, and molecular/cellular pathways that underlie human pain transduction, transmission, and processing. This FOA will support concerted multidisciplinary team science efforts that apply large-scale high-throughput approaches on tissues involved in human pain processing as part of the NIH HEAL Initiatives Program to Reveal and Evaluate Cells-to-gene Information that Specify Intricacies, Origins, and the Nature of Human Pain (PRECISION Human Pain). U19 Centers will operate as a cooperative network to promote collaboration and coordination of research activities. U19 Centers will also coordinate with the U24 HEAL Initiative: Human Pain-associated Genes and Cells Data Coordination and Integration Center in order to curate, harmonize, and integrate datasets generated by this U19 research program. |
Link to Additional Information: | http://grants.nih.gov/grants/guide/rfa-files/RFA-NS-22-018.html |
Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
OERWebmaster03@od.nih.gov Email:OERWebmaster03@od.nih.gov |
Version History
Version | Modification Description | Updated Date |
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Related Documents
There are no related documents on this grant.
Packages
Agency Contact Information: | NIH OER Webmaster OERWebmaster03@od.nih.gov Email: OERWebmaster03@od.nih.gov |
Who Can Apply: | Organization Applicants |
Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
---|---|---|---|---|---|---|
FORMS-G | Use for due dates on or before January 24, 2023 | PKG00271919 | Feb 17, 2022 | Jan 24, 2023 | View | |
FORMS-H | Use for due dates on or after January 25, 2023 | PKG00277521 | Oct 27, 2022 | Mar 09, 2023 | View |
Package 1
Mandatory forms
337841 RR_SF424_5_0-5.0.pdf
337841 PHS398_CoverPageSupplement_5_0-5.0.pdf
337841 RR_OtherProjectInfo_1_4-1.4.pdf
337841 PerformanceSite_4_0-4.0.pdf
337841 RR_KeyPersonExpanded_4_0-4.0.pdf
337841 PHS398_ResearchPlan_4_0-4.0.pdf
337841 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
337841 PHS_Additional_IndirectCosts_2_0-2.0.pdf
337841 PHS_AssignmentRequestForm_3_0-3.0.pdf
Package 2
Mandatory forms
337841 RR_SF424_5_0-5.0.pdf
337841 PHS398_CoverPageSupplement_5_0-5.0.pdf
337841 RR_OtherProjectInfo_1_4-1.4.pdf
337841 PerformanceSite_4_0-4.0.pdf
337841 RR_KeyPersonExpanded_4_0-4.0.pdf
337841 PHS398_ResearchPlan_5_0-5.0.pdf
337841 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
337841 PHS_Additional_IndirectCosts_2_0-2.0.pdf
337841 PHS_AssignmentRequestForm_3_0-3.0.pdf