National Institute on Aging Clinical Trial Grant: Fall Injury Prevention Strategy for Older Persons

The National Institute on Aging is offering a grant to conduct a clinical trial testing a multifactorial strategy for preventing serious fall-related injuries in older individuals living outside of institutions. The study should focus on designing a potent intervention to reduce fall injuries and should include screening, risk assessment, intervention selection, coordination, monitoring, and adaptive elements. Applicants are encouraged to incorporate patient and stakeholder input in the study design. The grant aims to identify effective fall prevention strategies that can be easily implemented in various care settings. Closing date for applications is November 13, 2013.

Opportunity ID: 237725

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General Information

Document Type::	Grants Notice
Funding Opportunity Number::	RFA-AG-14-009
Funding Opportunity Title::	Clinical Trial of a Multifactorial Fall Injury Prevention Strategy in Older Persons (U01)
Opportunity Category::	Discretionary
Opportunity Category Explanation::
Funding Instrument Type::
Category of Funding Activity::	Health
Category Explanation::
Expected Number of Awards::	1
Assistance Listings Number(s)::	93.866 — Aging Research
Cost Sharing or Matching Requirement::	No
Version::	Synopsis 1
Posted Date::	Jul 16, 2013
Last Updated Date::
Original Closing Date for Applications::	Nov 13, 2013
Current Closing Date for Applications::	Nov 13, 2013
Archive Date::	Dec 14, 2013
Estimated Total Program Funding::	$ 30,000,000
Award Ceiling::	$
Award Floor::	$

Eligibility

Eligible Applicants::

Others (see text field entitled “Additional Information on Eligibility” for clarification)

Additional Information on Eligibility::

Other Eligible Applicants include the following:
Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply.
Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.

Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.

Additional Information

Agency Name::	National Institutes of Health
Description::	This initiative invites applications for funding to conduct a randomized clinical trial of a multifactorial strategy for preventing serious fall-related injuries among non-institutionalized older persons. A multifactorial strategy should be designed for maximal potency in reducing the rate of serious fall-related injuries, which (if found to be effective in the trial) is feasible for future implementation with fidelity in practice in at least one type of care setting. The trial should test an evidence-based protocol that articulates decision rules that address: screening the population to identify individuals at high risk for falling, assessing high-risk individuals to define their specific risk factors, selecting interventions to ameliorate each persons risk factors, implementing these interventions, coordinating the delivery of each persons set of interventions (including methods for coordinating decisions on possible adjustments in medication prescribing among multiple prescribers for a given patient), monitoring each persons progress toward risk factor reduction, and implementing alternative interventions to overcome lack of progress and mitigate new risk factors. The study should incorporate patients and other relevant stakeholders priorities and perspectives in the specification of the study protocol and the outcomes to be measured. Applicants should consider adaptive study design features that facilitate “learning” from accumulating positive or negative evidence.
Link to Additional Information::
Grantor Contact Information::	If you have difficulty accessing the full announcement electronically, please contact:

Version History

Version	Modification Description	Updated Date
Synopsis 1

Package Status

Below are CLOSED Opportunity Package(s) no longer available for this Funding Opportunity:

Package No: 1

Assistance Listings:	93.866
Competition ID:	FORMS-C
Competition Title:	Forms-C
Opportunity Package ID:	PKG00181034
Opening Date:	Oct 13, 2013
Closing Date:	Nov 13, 2013
Agency Contact Information::	eRA Commons Help Desk
Who Can Apply::	Organization Applicants
mendatory_forms	SF424 (R & R) [V2.0] PHS 398 Research Plan [V2.0] PHS 398 Cover Page Supplement [V2.0] Research and Related Senior/Key Person Profile (Expanded) [V2.0] Research And Related Other Project Information [V1.3] Project/Performance Site Location(s) [V2.0]
optional_forms	R & R Subaward Budget Attachment(s) Form 5 YR 30 ATT [V1.3] Planned Enrollment Report [V1.0] PHS 398 Cumulative Inclusion Enrollment Report [V1.0] PHS 398 Modular Budget [V1.2] Research & Related Budget [V1.3]