This grant is for supporting novel, mechanistic studies on cytosolic DNA sensing mechanisms and their role in the interactions of aging hallmarks. Its primary purpose is to deepen the understanding of how cytosolic DNAs impact aging processes and longevity. The goal is to gain new insights into the critical role of aging hallmarks in healthy aging and age-related diseases. Innovative approaches are encouraged to identify and characterize how cytosolic DNA-mediated interactions of aging hallmarks modulate healthspan and overall longevity. This research will provide crucial knowledge to advance therapeutic strategies for age-related conditions.
Opportunity ID: 338343
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-AG-23-015 |
| Funding Opportunity Title: | Studies of Cytosolic DNAs in the Interactions of Aging Hallmarks (R01 Clinical Trial Not Allowed) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.866 — Aging Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Feb 25, 2022 |
| Last Updated Date: | Feb 25, 2022 |
| Original Closing Date for Applications: | Oct 11, 2022 |
| Current Closing Date for Applications: | Oct 11, 2022 |
| Archive Date: | Nov 16, 2022 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Private institutions of higher education Others (see text field entitled “Additional Information on Eligibility” for clarification) Independent school districts Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education County governments Native American tribal governments (Federally recognized) Public housing authorities/Indian housing authorities City or township governments State governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Small businesses Special district governments Native American tribal organizations (other than Federally recognized tribal governments) Public and State controlled institutions of higher education For profit organizations other than small businesses |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | This Funding Opportunity Announcement (FOA) invites applications on novel studies of the cytosolic DNA sensing mechanisms in the interactions of the aging hallmarks. The goal of this FOA is to support applications that will lead to an in-depth understanding of the molecular mechanisms that determine the effects of cytosolic DNAs on aging hallmarks in the context of aging and longevity. Research supported by this FOA should lead to new insights to address some critical mechanistic questions relevant to the role of aging hallmarks in aging and aging-related diseases. This FOA encourages innovative, mechanistic approaches to identify and characterize interactions of aging hallmarks mediated by cytosolic DNAs that ultimately modulate the regulation of healthspan and/or longevity. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/rfa-files/RFA-AG-23-015.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
OERWebmaster03@od.nih.gov Email:OERWebmaster03@od.nih.gov |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
There are no related documents on this grant.
Packages
| Agency Contact Information: | NIH OER Webmaster OERWebmaster03@od.nih.gov Email: OERWebmaster03@od.nih.gov |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-G | Use for due dates on or after January 25, 2022 | PKG00272222 | Sep 11, 2022 | Oct 11, 2022 | View |
Package 1
Mandatory forms
338343 RR_SF424_5_0-5.0.pdf
338343 PHS398_CoverPageSupplement_5_0-5.0.pdf
338343 RR_OtherProjectInfo_1_4-1.4.pdf
338343 PerformanceSite_4_0-4.0.pdf
338343 RR_KeyPersonExpanded_4_0-4.0.pdf
338343 PHS398_ResearchPlan_4_0-4.0.pdf
338343 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
338343 RR_Budget_3_0-3.0.pdf
338343 RR_SubawardBudget30_3_0-3.0.pdf
338343 PHS398_ModularBudget_1_2-1.2.pdf
338343 PHS_AssignmentRequestForm_3_0-3.0.pdf
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