The National Eye Institute (NEI) is offering this Regenerative Medicine Clinical Trial Planning Grant as part of its Audacious Goal Initiative. This grant is for the purpose of advancing vision restoration by regenerating crucial cells in the retina. Specifically, the initiative targets photoreceptors and retinal ganglion cells, which are essential for processing and transmitting visual signals to the brain. While encouraging success has been observed in regenerating retinal neurons in animal models, the ultimate aim of this NEI grant is to support the planning phases of clinical trials, paving the way for restoring human vision through regenerative approaches.
Opportunity ID: 338605
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | PAR-22-135 |
| Funding Opportunity Title: | NEI Regenerative Medicine Clinical Trial Planning Grant (R34 – Clinical Trials Not Allowed) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.867 — Vision Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 2 |
| Posted Date: | Mar 08, 2022 |
| Last Updated Date: | Dec 19, 2024 |
| Original Closing Date for Applications: | May 07, 2025 |
| Current Closing Date for Applications: | Dec 19, 2024 |
| Archive Date: | Jan 18, 2025 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | $150,000 |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Public and State controlled institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Small businesses City or township governments For profit organizations other than small businesses Others (see text field entitled “Additional Information on Eligibility” for clarification) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Independent school districts Private institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments) County governments Public housing authorities/Indian housing authorities State governments Native American tribal governments (Federally recognized) Special district governments |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: |
The National Eye Institute (NEI) Audacious Goal Initiative (AGI) is an effort to push the boundaries of vision science and restore vision through regeneration of cells in the retina. AGI research specifically targets photoreceptors (PRCs) and retinal ganglion cells (RGCs) in the eye. Photoreceptors often called rods and cones are cells in the retina that, when stimulated by light, generate signals the brain perceives as images. The retinal ganglion cells carry these signals from the photoreceptors to the brain. Although there has been some success in regenerating retinal neurons and connections in fish, mice, and other systems, the ultimate goal of the AGI is to restore vision in humans. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/pa-files/PAR-22-135.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
OERWebmaster03@od.nih.gov Email:OERWebmaster03@od.nih.gov |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
| updated close date | Dec 19, 2024 | |
| Mar 08, 2022 |
DISPLAYING: Synopsis 2
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | PAR-22-135 |
| Funding Opportunity Title: | NEI Regenerative Medicine Clinical Trial Planning Grant (R34 – Clinical Trials Not Allowed) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.867 — Vision Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 2 |
| Posted Date: | Mar 08, 2022 |
| Last Updated Date: | Dec 19, 2024 |
| Original Closing Date for Applications: | May 07, 2025 |
| Current Closing Date for Applications: | Dec 19, 2024 |
| Archive Date: | Jan 18, 2025 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | $150,000 |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Public and State controlled institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Small businesses City or township governments For profit organizations other than small businesses Others (see text field entitled “Additional Information on Eligibility” for clarification) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Independent school districts Private institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments) County governments Public housing authorities/Indian housing authorities State governments Native American tribal governments (Federally recognized) Special district governments |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: |
The National Eye Institute (NEI) Audacious Goal Initiative (AGI) is an effort to push the boundaries of vision science and restore vision through regeneration of cells in the retina. AGI research specifically targets photoreceptors (PRCs) and retinal ganglion cells (RGCs) in the eye. Photoreceptors often called rods and cones are cells in the retina that, when stimulated by light, generate signals the brain perceives as images. The retinal ganglion cells carry these signals from the photoreceptors to the brain. Although there has been some success in regenerating retinal neurons and connections in fish, mice, and other systems, the ultimate goal of the AGI is to restore vision in humans. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/pa-files/PAR-22-135.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
OERWebmaster03@od.nih.gov Email:OERWebmaster03@od.nih.gov |
DISPLAYING: Synopsis 1
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | PAR-22-135 |
| Funding Opportunity Title: | NEI Regenerative Medicine Clinical Trial Planning Grant (R34 – Clinical Trials Not Allowed) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.867 — Vision Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Mar 08, 2022 |
| Last Updated Date: | Mar 08, 2022 |
| Original Closing Date for Applications: | – |
| Current Closing Date for Applications: | May 07, 2025 |
| Archive Date: | Jun 12, 2025 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | $150,000 |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Native American tribal organizations (other than Federally recognized tribal governments) Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education For profit organizations other than small businesses Independent school districts Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Small businesses Public housing authorities/Indian housing authorities Native American tribal governments (Federally recognized) Others (see text field entitled “Additional Information on Eligibility” for clarification) Public and State controlled institutions of higher education County governments Special district governments Private institutions of higher education City or township governments State governments |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | The National Eye Institute (NEI) Audacious Goal Initiative (AGI) is an effort to push the boundaries of vision science and restore vision through regeneration of cells in the retina. AGI research specifically targets photoreceptors (PRCs) and retinal ganglion cells (RGCs) in the eye. Photoreceptors often called rods and cones are cells in the retina that, when stimulated by light, generate signals the brain perceives as images. The retinal ganglion cells carry these signals from the photoreceptors to the brain. Although there has been some success in regenerating retinal neurons and connections in fish, mice, and other systems, the ultimate goal of the AGI is to restore vision in humans. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/pa-files/PAR-22-135.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
OERWebmaster03@od.nih.gov Email:OERWebmaster03@od.nih.gov |
Related Documents
Folder 338605 Full Announcement-PAR-22-135 -> PAR-22-135-Full-Announcement.pdf
Packages
| Agency Contact Information: | NIH OER Webmaster OERWebmaster03@od.nih.gov Email: OERWebmaster03@od.nih.gov |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-G | Use for due dates on or before January 24, 2023 | PKG00272473 | May 16, 2022 | Jan 24, 2023 | View | |
| FORMS-H | Use for due dates on or before January 24, 2025 | PKG00278278 | Nov 10, 2022 | Dec 20, 2024 | View | |
| FORMS-I | Use for due dates on or after January 25, 2025 | PKG00289005 | Nov 25, 2024 | Dec 20, 2024 | View |
Package 1
Mandatory forms
338605 RR_SF424_5_0-5.0.pdf
338605 PHS398_CoverPageSupplement_5_0-5.0.pdf
338605 RR_OtherProjectInfo_1_4-1.4.pdf
338605 PerformanceSite_4_0-4.0.pdf
338605 RR_KeyPersonExpanded_4_0-4.0.pdf
338605 PHS398_ResearchPlan_4_0-4.0.pdf
338605 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
338605 RR_Budget_3_0-3.0.pdf
338605 RR_SubawardBudget30_3_0-3.0.pdf
338605 PHS398_ModularBudget_1_2-1.2.pdf
338605 PHS_AssignmentRequestForm_3_0-3.0.pdf
Package 2
Mandatory forms
338605 RR_SF424_5_0-5.0.pdf
338605 PHS398_CoverPageSupplement_5_0-5.0.pdf
338605 RR_OtherProjectInfo_1_4-1.4.pdf
338605 PerformanceSite_4_0-4.0.pdf
338605 RR_KeyPersonExpanded_4_0-4.0.pdf
338605 PHS398_ResearchPlan_5_0-5.0.pdf
338605 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
338605 RR_Budget_3_0-3.0.pdf
338605 RR_SubawardBudget30_3_0-3.0.pdf
338605 PHS398_ModularBudget_1_2-1.2.pdf
338605 PHS_AssignmentRequestForm_3_0-3.0.pdf
Package 3
Mandatory forms
338605 RR_SF424_5_0-5.0.pdf
338605 PHS398_CoverPageSupplement_5_0-5.0.pdf
338605 RR_OtherProjectInfo_1_4-1.4.pdf
338605 PerformanceSite_4_0-4.0.pdf
338605 RR_KeyPersonExpanded_4_0-4.0.pdf
338605 PHS398_ResearchPlan_5_0-5.0.pdf
338605 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
338605 RR_Budget_3_0-3.0.pdf
338605 RR_SubawardBudget30_3_0-3.0.pdf
338605 PHS398_ModularBudget_1_2-1.2.pdf
338605 PHS_AssignmentRequestForm_4_0-4.0.pdf
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