This grant is for the critical purpose of stimulating the development of novel model systems and comprehensively characterizing the ovarian phenotype of current models relevant to Fragile X associated premature ovarian insufficiency (FX-POI). The availability of new and well-understood FX-POI models is essential. They will enable researchers to delve into fundamental questions concerning the specific role of the FMR1 repeat expansion in complex processes such as ovarian function and reproductive aging. Furthermore, this initiative aims to significantly advance the field, paving the way for robust, evidence-based clinical research specifically targeting fragile X pre-mutation carriers, who face an elevated risk of developing POI. This will ultimately enhance understanding and lead to better clinical approaches.
Opportunity ID: 77533
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | PAR-11-137 |
| Funding Opportunity Title: | Model Systems for Fragile X Pre-Mutation and Primary Ovarian Insufficiency (FX-POI) (R21) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Health Income Security and Social Services |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.865 — Child Health and Human Development Extramural Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Mar 09, 2011 |
| Last Updated Date: | – |
| Original Closing Date for Applications: | Jun 01, 2012 |
| Current Closing Date for Applications: | Jun 01, 2012 |
| Archive Date: | Jul 02, 2012 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | $200,000 |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Public housing authorities/Indian housing authorities Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Public and State controlled institutions of higher education Private institutions of higher education State governments County governments Independent school districts Others (see text field entitled “Additional Information on Eligibility” for clarification) Native American tribal governments (Federally recognized) For profit organizations other than small businesses Small businesses City or township governments Special district governments |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Foreign (non-U.S.) components of U.S. Organizations are allowed. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | The purpose of this funding opportunity announcement (FOA) is to stimulate the development of new model systems and/or the thorough characterization of the ovarian phenotype of existing models of fragile X associated premature ovarian insufficiency (FX-POI). New and well-characterized models of FX-POI will help us to answer fundamental questions about the role of the FMR1 repeat expansion in ovarian function and reproductive aging, and allow the field to advance into evidence based clinical research on fragile X pre-mutation carriers who are at risk for POI. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/pa-files/PAR-11-137.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV Email:FBOWebmaster@OD.NIH.GOV |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
There are no related documents on this grant.
Packages
| Agency Contact Information: | NIH OER Webmaster FBOWebmaster@OD.NIH.GOV Email: FBOWebmaster@OD.NIH.GOV |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| 93.865 | ADOBE-FORMS-B1 | ADOBE-FORMS-B1 | PKG00039190 | May 01, 2011 | Jun 01, 2012 | View |
Package 1
Mandatory forms
77533 RR_SF424_1_2-1.2.pdf
77533 RR_OtherProjectInfo_1_3-1.3.pdf
77533 RR_KeyPersonExpanded_1_2-1.2.pdf
77533 PerformanceSite_1_4-1.4.pdf
77533 PHS398_ResearchPlan_1_3-1.3.pdf
77533 PHS398_CoverPageSupplement_1_4-1.4.pdf
77533 PHS398_Checklist_1_3-1.3.pdf
Optional forms
77533 RR_Budget-1.1.pdf
77533 RR_SubawardBudget-1.2.pdf
77533 PHS_CoverLetter_1_2-1.2.pdf
77533 PHS398_ModularBudget-1.1.pdf
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