The National Institute of Neurological Disorders and Stroke (NINDS) is offering this cooperative grant to support advanced pre-clinical development and testing of new therapies for neurological disorders. This grant is for accelerating the translation of basic research discoveries into therapeutic candidates ready for clinical testing. It specifically targets projects with therapeutic leads demonstrating proven activity against a disease target, supporting their optimization and testing. The primary goal is the submission of an IND or IDE application to the FDA by the project’s conclusion. This is a milestone-driven program involving direct participation from NINDS staff, but it explicitly excludes early-stage therapeutic discovery, clinical research, basic research, and studies focusing solely on disease mechanisms.
Opportunity ID: 78893
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | PAR-11-153 |
| Funding Opportunity Title: | NINDS Cooperative Program in Translational Research Single-Component Research Projects (U01) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Cooperative Agreement |
| Category of Funding Activity: | Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.853 — Extramural Research Programs in the Neurosciences and Neurological Disorders |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Mar 15, 2011 |
| Last Updated Date: | – |
| Original Closing Date for Applications: | Sep 07, 2011 |
| Current Closing Date for Applications: | Sep 07, 2011 |
| Archive Date: | Oct 08, 2011 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | City or township governments Native American tribal organizations (other than Federally recognized tribal governments) Private institutions of higher education County governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Others (see text field entitled “Additional Information on Eligibility” for clarification) Independent school districts Special district governments State governments Public and State controlled institutions of higher education Native American tribal governments (Federally recognized) Public housing authorities/Indian housing authorities Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education For profit organizations other than small businesses Small businesses |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Foreign (non-U.S.) components of U.S. Organizations are allowed. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | The goal of this funding opportunity announcement (FOA) is to support pre-clinical development and testing of new therapies for neurological disorders. The program will facilitate solicitation, development, and review of therapy-directed projects to accelerate the translation of basic research discoveries into therapeutic candidates for clinical testing. This program is specifically directed at projects that include therapeutic leads with demonstrated activity against the intended disease target. The program supports pre-clinical optimization and testing of these leads and projects must be sufficiently advanced that an IND or IDE application to the FDA can be submitted by the end of the project period. The program does not support early-stage therapeutic discovery activities such as high throughput screening. The program also excludes clinical research, basic research, and studies of disease mechanism. This is a milestone-driven cooperative agreement program involving participation of NINDS staff in the development of the project plan and monitoring of research progress. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/pa-files/PAR-11-153.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV Email:FBOWebmaster@OD.NIH.GOV |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
There are no related documents on this grant.
Packages
| Agency Contact Information: | NIH OER Webmaster FBOWebmaster@OD.NIH.GOV Email: FBOWebmaster@OD.NIH.GOV |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| 93.853 | ADOBE-FORMS-B1 | ADOBE-FORMS-B1 | PKG00043470 | May 05, 2011 | Sep 07, 2011 | View |
Package 1
Mandatory forms
78893 RR_SF424_1_2-1.2.pdf
78893 RR_OtherProjectInfo_1_3-1.3.pdf
78893 RR_KeyPersonExpanded_1_2-1.2.pdf
78893 PerformanceSite_1_4-1.4.pdf
78893 PHS398_ResearchPlan_1_3-1.3.pdf
78893 PHS398_CoverPageSupplement_1_4-1.4.pdf
78893 PHS398_Checklist_1_3-1.3.pdf
Optional forms
78893 RR_Budget-1.1.pdf
78893 RR_SubawardBudget-1.2.pdf
78893 PHS_CoverLetter_1_2-1.2.pdf
78893 PHS398_ModularBudget-1.1.pdf
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