This grant opportunity from the NIH is for organizations proposing to develop and implement interventions to remediate age-related cognitive decline. A crucial feature is embedding intervention testing into a comprehensive measurement framework. This framework must elucidate the intervention’s mechanism of action, identify individuals most likely to benefit, and examine adaptive plastic changes in the central nervous system (CNS). Furthermore, the research should investigate whether these neural changes explain the observed patterns of cognitive improvement. While projects may include an observational component, all developed interventions must be rigorously tested within a randomized clinical trial (RCT) design.
Opportunity ID: 249676
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-AG-14-016 |
| Funding Opportunity Title: | Plasticity and Mechanisms of Cognitive Remediation in Older Adults (R01) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.213 — Research and Training in Complementary and Alternative Medicine |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Jan 03, 2014 |
| Last Updated Date: | – |
| Original Closing Date for Applications: | Mar 04, 2014 |
| Current Closing Date for Applications: | Mar 04, 2014 |
| Archive Date: | Apr 04, 2014 |
| Estimated Total Program Funding: | $3,000,000 |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | City or township governments Independent school districts Public and State controlled institutions of higher education Public housing authorities/Indian housing authorities Small businesses State governments Private institutions of higher education Native American tribal governments (Federally recognized) County governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education For profit organizations other than small businesses Special district governments Others (see text field entitled “Additional Information on Eligibility” for clarification) Native American tribal organizations (other than Federally recognized tribal governments) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | This funding opportunity announcement (FOA) solicits R01 grant applications from applicant organizations that propose to develop and implement interventions to remediate age-related cognitive decline. A crucial feature of these applications will be the embedding of the testing of the proposed intervention into a measurement framework that will: 1) help elucidate its mechanism of action; 2) identify specific individuals who are more likely or less likely to benefit from the intervention, and 3) examine whether adaptive plastic changes have occurred in the structure or function of the CNS as a result of the intervention, and whether these neural changes help explain the pattern of improvement seen in cognitive functioning. Although projects may include an observational component, the interventions developed should be tested in a randomized clinical trial (RCT). |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/rfa-files/RFA-AG-14-016.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV Email:FBOWebmaster@OD.NIH.GOV |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
There are no related documents on this grant.
Packages
| Agency Contact Information: | NIH OER Webmaster FBOWebmaster@OD.NIH.GOV Email: FBOWebmaster@OD.NIH.GOV |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-C | Forms-C | PKG00191491 | Feb 04, 2014 | Mar 04, 2014 | View |
Package 1
Mandatory forms
249676 RR_SF424_2_0-2.0.pdf
249676 PHS398_ResearchPlan_2_0-2.0.pdf
249676 PHS398_CoverPageSupplement_2_0-2.0.pdf
249676 RR_KeyPersonExpanded_2_0-2.0.pdf
249676 RR_OtherProjectInfo_1_3-1.3.pdf
249676 PerformanceSite_2_0-2.0.pdf
Optional forms
249676 RR_SubawardBudget30_1_3-1.3.pdf
249676 PlannedReport-1.0.pdf
249676 PHS398_CumulativeInclusionReport-1.0.pdf
249676 PHS398_ModularBudget_1_2-1.2.pdf
249676 RR_Budget_1_3-1.3.pdf
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