This National Institutes of Health (NIH) grant is for the critical purpose of advancing NeuroHIV research. It seeks applications proposing the development and early-stage validation of innovative preclinical models. The focus is on creating next-generation humanized small animal models or human cellular microphysiological systems. These models must significantly enhance the translational relevance of NeuroHIV studies, particularly concerning chronic HIV infection within the central nervous system during the modern antiretroviral therapy (ART) era. The initiative emphasizes research under conditions of effective viral suppression, aiming to bridge the gap between current models and the realities of living with HIV today. This funding will support foundational work for improved understanding and treatment strategies.
Opportunity ID: 355119
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-NS-24-035 |
| Funding Opportunity Title: | Novel Preclinical Models of NeuroHIV in the cART Era (R61/R33 – Clinical Trial Not Allowed) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Education Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.242 — Mental Health Research Grants |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Jun 25, 2024 |
| Last Updated Date: | Jun 25, 2024 |
| Original Closing Date for Applications: | Dec 02, 2024 |
| Current Closing Date for Applications: | Dec 02, 2024 |
| Archive Date: | Jan 07, 2025 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | $600,000 |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | City or township governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Special district governments County governments Public housing authorities/Indian housing authorities State governments Independent school districts Private institutions of higher education Public and State controlled institutions of higher education Native American tribal governments (Federally recognized) Native American tribal organizations (other than Federally recognized tribal governments) Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education For profit organizations other than small businesses Others (see text field entitled “Additional Information on Eligibility” for clarification) Small businesses |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | This initiative will solicit applications that propose the development and early stage validation of next generation humanized small animal models and/or human cellular microphysiological systems that improve the translational relevance of NeuroHIV models, specifically in the context of chronic HIV infection of the CNS in the modern antiretroviral therapy (ART) era under conditions of viral suppression. |
| Link to Additional Information: | https://grants.nih.gov/grants/guide/rfa-files/RFA-NS-24-035.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH Grants Information
grantsinfo@nih.gov Email:grantsinfo@nih.gov |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
Folder 355119 Full Announcement-RFA-NS-24-035 -> RFA-NS-24-035-Full-Announcement.pdf
Packages
| Agency Contact Information: | NIH Grants Information grantsinfo@nih.gov Email: grantsinfo@nih.gov |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-H | Use for due dates on or before January 24, 2025 | PKG00287168 | Nov 01, 2024 | Jan 24, 2025 | View |
Package 1
Mandatory forms
355119 RR_SF424_5_0-5.0.pdf
355119 PHS398_CoverPageSupplement_5_0-5.0.pdf
355119 RR_OtherProjectInfo_1_4-1.4.pdf
355119 PerformanceSite_4_0-4.0.pdf
355119 RR_KeyPersonExpanded_4_0-4.0.pdf
355119 RR_Budget10_3_0-3.0.pdf
355119 PHS398_ResearchPlan_5_0-5.0.pdf
355119 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
355119 RR_SubawardBudget10_30_3_0-3.0.pdf
355119 PHS_AssignmentRequestForm_3_0-3.0.pdf
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