This grant is for the purpose of supporting fundamental studies that identify and define the molecular mechanisms by which lipid metabolism mediates tumor growth and progression. It specifically focuses on the central role lipids play in linking diet with cancer biology, aiming to bridge the historically divided fields of nutrition and molecular metabolism. The grant also seeks to stimulate innovative research and tool development in this emerging area, acknowledging the challenges presented by the complexity of lipid biochemistry.
Opportunity ID: 356922
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | PAR-25-119 |
| Funding Opportunity Title: | Mechanistic links between diet, lipid metabolism, and tumor growth and progression (U01 Clinical Trial Not Allowed) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Cooperative Agreement |
| Category of Funding Activity: | Education Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.393 — Cancer Cause and Prevention Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Oct 31, 2024 |
| Last Updated Date: | Oct 31, 2024 |
| Original Closing Date for Applications: | Oct 23, 2025 |
| Current Closing Date for Applications: | Oct 23, 2025 |
| Archive Date: | Nov 28, 2025 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Private institutions of higher education Public housing authorities/Indian housing authorities For profit organizations other than small businesses State governments Native American tribal governments (Federally recognized) County governments Small businesses Native American tribal organizations (other than Federally recognized tribal governments) City or township governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Special district governments Public and State controlled institutions of higher education Others (see text field entitled “Additional Information on Eligibility” for clarification) Independent school districts |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | Through this Notice of Funding Opportunity (NOFO) is to request applications that propose mechanistic investigations of the links between diet, lipid metabolism and tumor growth and progression. It is anticipated that this program will support fundamental studies designed to identify and define the molecular mechanisms through which lipid metabolism mediates tumor growth and progression, focusing specifically on the central role lipids play in linking diet with the biology of cancer; bridge the historically divided fields of nutrition and molecular metabolism; and stimulate research and tool development in this emerging area, which faces particular challenges because of the complexity of lipid biochemistry. |
| Link to Additional Information: | https://grants.nih.gov/grants/guide/pa-files/PAR-25-119.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH Grants Information
grantsinfo@nih.gov Email:grantsinfo@nih.gov |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
Folder 356922 Full Announcement-PAR-25-119 -> PAR-25-119-Full-Announcement.pdf
Packages
| Agency Contact Information: | NIH Grants Information grantsinfo@nih.gov Email: grantsinfo@nih.gov |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-I | Use for due dates on or after January 25, 2025 | PKG00288340 | Jan 14, 2025 | Oct 23, 2025 | View |
Package 1
Mandatory forms
356922 RR_SF424_5_0-5.0.pdf
356922 PHS398_CoverPageSupplement_5_0-5.0.pdf
356922 RR_OtherProjectInfo_1_4-1.4.pdf
356922 PerformanceSite_4_0-4.0.pdf
356922 RR_KeyPersonExpanded_4_0-4.0.pdf
356922 PHS398_ResearchPlan_5_0-5.0.pdf
356922 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
356922 RR_Budget_3_0-3.0.pdf
356922 RR_SubawardBudget30_3_0-3.0.pdf
356922 PHS398_ModularBudget_1_2-1.2.pdf
356922 PHS_AssignmentRequestForm_4_0-4.0.pdf
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