This NIH Notice of Funding Opportunity (NOFO) aims to stimulate research focused on brain disorders. The grant seeks to fund projects involved in the discovery and development of novel small molecules. These molecules are intended for potential use in studying and treating psychiatric disorders. A key objective is also to generate new insights into the fundamental biology of relevant diseases and processes. This includes exploring biological mechanisms that have not yet been validated as important drug targets, thereby expanding our understanding and potential therapeutic avenues for complex brain conditions. The overall goal is to advance the understanding and treatment of neurological and psychiatric conditions through innovative chemical approaches.
Opportunity ID: 357020
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | PAR-25-063 |
| Funding Opportunity Title: | Assay Development and Screening for Discovery of Validated Chemical Hits for Brain Disorders (R01 Clinical Trial Not Allowed) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.242 — Mental Health Research Grants |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Nov 06, 2024 |
| Last Updated Date: | Nov 06, 2024 |
| Original Closing Date for Applications: | May 07, 2026 |
| Current Closing Date for Applications: | May 07, 2026 |
| Archive Date: | Jun 12, 2026 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | State governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Public and State controlled institutions of higher education Others (see text field entitled “Additional Information on Eligibility” for clarification) Native American tribal governments (Federally recognized) Small businesses City or township governments For profit organizations other than small businesses Public housing authorities/Indian housing authorities Independent school districts Private institutions of higher education County governments Native American tribal organizations (other than Federally recognized tribal governments) Special district governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | The objective of this Notice of Funding Opportunity (NOFO) is to stimulate research in 1) discovery and development of novel, small molecules for their potential use in studying disease treatment relevant to psychiatric disorders; and 2) to generate new insight into the biology of relevant diseases and processes that have yet to be validated as important drug targets. |
| Link to Additional Information: | https://grants.nih.gov/grants/guide/pa-files/PAR-25-063.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH Grants Information
grantsinfo@nih.gov Email:grantsinfo@nih.gov |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
Folder 357020 Full Announcement-PAR-25-063 -> PAR-25-063-Full-Announcement.pdf
Packages
| Agency Contact Information: | NIH Grants Information grantsinfo@nih.gov Email: grantsinfo@nih.gov |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-I | Use for due dates on or after January 25, 2025 | PKG00288558 | Jan 05, 2025 | May 07, 2026 | View |
Package 1
Mandatory forms
357020 RR_SF424_5_0-5.0.pdf
357020 PHS398_CoverPageSupplement_5_0-5.0.pdf
357020 RR_OtherProjectInfo_1_4-1.4.pdf
357020 PerformanceSite_4_0-4.0.pdf
357020 RR_KeyPersonExpanded_4_0-4.0.pdf
357020 PHS398_ResearchPlan_5_0-5.0.pdf
357020 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
357020 RR_Budget_3_0-3.0.pdf
357020 RR_SubawardBudget30_3_0-3.0.pdf
357020 PHS398_ModularBudget_1_2-1.2.pdf
357020 PHS_AssignmentRequestForm_4_0-4.0.pdf
Share This Post, Choose Your Platform!
About the Author: osnqt
