DoD Investigator-Initiated Grant for Translational Research in Duchenne Muscular Dystrophy

Studies proposed under this award should not include:

• Target discovery

• Drug screening

• Mechanism of action studies

All applications must include preliminary data that are relevant to Duchenne and the proposed project. Clinical trials are supported by this award mechanism and, if proposed, require the submission of Attachment 12: Human Subject Recruitment and Safety Procedures.

Optional Features: The IIRA mechanism allows for the inclusion of the following options, which would allow the applicant to request additional funds as described in Section II.D.5, Funding Restrictions. The Government reserves the right to fund an application at a lower funding level if it does not meet the eligibility criteria or intent of the optional feature(s).

Optional Multidiscipline Collaborator (OMC): The FY17 DMDRP strongly encourages multidisciplinary collaborations among academic scientists and clinicians, industry scientists, the military Services, the Department of Veterans Affairs, and other Federal government agencies. The goal of the OMC is to bring new perspectives from other disciplines or bring new investigators into the Duchenne field by supporting projects that include multidisciplinary collaborations including, but not limited to immunology, nanotechnology, or orthopaedics.

Optional Nested Resident or Medical Student Traineeship: The intent of the Nested Resident or Medical Student Traineeship is to provide mentored research opportunities in Duchenne. It is expected that the training will provide a valuable opportunity to develop the experience necessary to advance the trainee’s research career in Duchenne. Only one traineeship may be requested per application. Plans for training and mentorship must be well developed and clearly described by the PI in Attachment 9: Statement of Traineeship.